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On-resin N-formylation of peptides: a head-to-head comparison of reagents in solid-phase synthesis of ligands for formyl peptide receptors
Simon Bendt Christensen, Anna Mette Hansen,
Henrik Franzyk
Department of Drug Design and Pharmacology
2
Citations (Scopus)
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Medicine & Life Sciences
2,2,2-trifluoroethyl formate
1%
Esters
12%
ethyl formate
26%
Ethyldimethylaminopropyl Carbodiimide
21%
Formates
24%
formic acid
80%
Formic Acid Esters
27%
Formyl Peptide Receptor
89%
Heating
13%
Ligands
43%
Microwaves
14%
Peptides
39%
Solid-Phase Synthesis Techniques
100%
Temperature
8%
Tentagel resin
27%
Chemical Compounds
Ambient Reaction Temperature
5%
Aromatic Ester
14%
Carbodiimide
11%
Ester
6%
Ethyl Formate
15%
Formate
62%
Formic Acid
9%
Formylation
40%
Ligand
27%
Peptide
35%
Reduction
4%
Solvent
4%
Time
11%