Abstract
OBJECTIVE: To assess obstetrical and neonatal outcomes in women following gastric bypass, compared with adipose women without surgery and with a normal weight control population.
DESIGN: Historical controlled cohort study.
SETTING: Denmark.
POPULATION: All women undergoing gastric bypass during the period 1996-2011, and subsequently giving birth.
METHODS AND MAIN OUTCOME MEASURES: Obstetrical and neonatal outcomes in women without gastric bypass matched on age, parity, plurality, year, and body mass index, and normal weight women.
RESULTS: In 415 women giving birth after gastric bypass we found significantly more women with hypertension in pregnancy; relative risk (RR) 2.5 (95% confidence interval 1.3-5.0), gestational diabetes; RR = 6.9 (3.5-13.5), and acute abdominal pain during pregnancy; RR = 4.7 (2.9-7.8) compared with normal weight controls. Compared with women with similar body mass index, they had a lower incidence of preeclampsia and emergency cesarean sections, and their children a lower incidence of asphyxia; RR = 0.4 (0.2-0.8). Their children were on average 212 g smaller than newborn of normal weight mothers, and 319 g smaller than newborn of adipose controls, and had significantly more admissions to neonatal intensive care unit compared with newborn of normal weight mothers; RR = 1.5 (1.1-2.0).
CONCLUSIONS: Gastric bypass may reduce the risk of preeclampsia, emergency cesarean section, and perinatal asphyxia, compared with adipose women without surgery. Compared with normal weight controls women who had had a gastric bypass had a higher risk of hypertension, gestational diabetes, and acute abdominal pain during pregnancy and their children a lower birthweight and higher incidence of admittance to neonatal intensive care.
| Original language | English |
|---|---|
| Journal | Acta Obstetrica et Gynecologica |
| Volume | 93 |
| Issue number | 5 |
| Pages (from-to) | 447-53 |
| Number of pages | 7 |
| ISSN | 0001-6349 |
| DOIs | |
| Publication status | Published - May 2014 |
Keywords
- Abdominal Pain
- Adolescent
- Adult
- Asphyxia Neonatorum
- Body Mass Index
- Case-Control Studies
- Cesarean Section
- Cohort Studies
- Denmark
- Diabetes, Gestational
- Female
- Gastric Bypass
- Humans
- Hypertension, Pregnancy-Induced
- Incidence
- Infant, Newborn
- Infant, Small for Gestational Age
- Middle Aged
- Obesity
- Pre-Eclampsia
- Pregnancy
- Pregnancy Complications
- Pregnancy Outcome
- Registries
- Young Adult
