Nye behandlingsmuligheder ved primær immun trombocytopeni

Translated title of the contribution: [New treatment options for primary immune thrombocytopenia]

Sif Gudbrandsdottir, Henrik Frederiksen, Henrik Sverre Birgens, Claus Henrik Nielsen, Ove Juul Nielsen, Jesper Stentoft, Hans Carl Hasselbalch

    1 Citation (Scopus)

    Abstract

    Primary immune thrombocytopenia (ITP)--formerly known as idiopathic thrombocytopenic purpura--is an autoimmune disorder characterized by immune mediated thrombocytopenia. The aetiology of ITP remains unknown, but studies have shown that multiple immunological mechanisms are involved in the pathogenesis of ITP. This article aims to provide an overview of current treatment options, with particular emphasis on new biological therapies: rituximab, a monoclonal anti-CD20 antibody, and the thrombopoietin receptor agonists romiplostim and eltrombopag.
    Translated title of the contribution[New treatment options for primary immune thrombocytopenia]
    Original languageDanish
    JournalUgeskrift for Laeger
    Volume173
    Issue number4
    Pages (from-to)271-4
    Number of pages4
    ISSN0041-5782
    Publication statusPublished - 24 Jan 2011

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