Ny markør ved trombotisk trombocytopenisk purpura.

Jens Peter Gøtze; Andreas Hillarp; Anders Lindblom; Peter Björk; Karin Strandberg; Lars Bo Nielsen

Ny markør ved trombotisk trombocytopenisk purpura.

Translated title of the contribution: New marker in thrombotic thrombocytopenic purpura

Jens Peter Gøtze, Andreas Hillarp, Anders Lindblom, Peter Björk, Karin Strandberg, Lars Bo Nielsen

Physiology of circulation, kidney and lung

2 Citations (Scopus)

Abstract

Thrombotic microangiopathy can be caused by several conditions which are difficult to diagnose from the clinical presentation alone. Deficient enzyme activity of a newly-discovered enzyme, ADAMTS-13, can lead to thrombotic thrombocytopenic purpura (TTP). Lack of ADAMTS-13 activity causes increased concentrations of high molecular weight von Willebrand factor forms and increased platelet aggregation. Measurement of ADAMTS-13 activity is useful for the diagnosis of TTP and may also be relevant as a prognostic test for recurrent TTP.
Udgivelsesdato: 2008-Aug-11

Translated title of the contribution	New marker in thrombotic thrombocytopenic purpura
Original language	Danish
Journal	Ugeskrift for læger
Volume	170
Issue number	33
Pages (from-to)	2446-9
Number of pages	3
ISSN	0041-5782
Publication status	Published - 2008

Cite this

@article{c895e0a0acd511ddb538000ea68e967b,

title = "Ny mark{\o}r ved trombotisk trombocytopenisk purpura.",

abstract = "Thrombotic microangiopathy can be caused by several conditions which are difficult to diagnose from the clinical presentation alone. Deficient enzyme activity of a newly-discovered enzyme, ADAMTS-13, can lead to thrombotic thrombocytopenic purpura (TTP). Lack of ADAMTS-13 activity causes increased concentrations of high molecular weight von Willebrand factor forms and increased platelet aggregation. Measurement of ADAMTS-13 activity is useful for the diagnosis of TTP and may also be relevant as a prognostic test for recurrent TTP. Udgivelsesdato: 2008-Aug-11",

author = "G{\o}tze, {Jens Peter} and Andreas Hillarp and Anders Lindblom and Peter Bj{\"o}rk and Karin Strandberg and Nielsen, {Lars Bo}",

note = "Keywords: ADAM Proteins; Biological Markers; Diagnosis, Differential; Humans; Purpura, Thrombotic Thrombocytopenic; von Willebrand Factor",

year = "2008",

language = "Dansk",

volume = "170",

pages = "2446--9",

journal = "Ugeskrift for Laeger",

issn = "0041-5782",

publisher = "Almindelige Danske Laegeforening",

number = "33",

}

TY - JOUR

T1 - Ny markør ved trombotisk trombocytopenisk purpura.

AU - Gøtze, Jens Peter

AU - Hillarp, Andreas

AU - Lindblom, Anders

AU - Björk, Peter

AU - Strandberg, Karin

AU - Nielsen, Lars Bo

N1 - Keywords: ADAM Proteins; Biological Markers; Diagnosis, Differential; Humans; Purpura, Thrombotic Thrombocytopenic; von Willebrand Factor

PY - 2008

Y1 - 2008

N2 - Thrombotic microangiopathy can be caused by several conditions which are difficult to diagnose from the clinical presentation alone. Deficient enzyme activity of a newly-discovered enzyme, ADAMTS-13, can lead to thrombotic thrombocytopenic purpura (TTP). Lack of ADAMTS-13 activity causes increased concentrations of high molecular weight von Willebrand factor forms and increased platelet aggregation. Measurement of ADAMTS-13 activity is useful for the diagnosis of TTP and may also be relevant as a prognostic test for recurrent TTP. Udgivelsesdato: 2008-Aug-11

AB - Thrombotic microangiopathy can be caused by several conditions which are difficult to diagnose from the clinical presentation alone. Deficient enzyme activity of a newly-discovered enzyme, ADAMTS-13, can lead to thrombotic thrombocytopenic purpura (TTP). Lack of ADAMTS-13 activity causes increased concentrations of high molecular weight von Willebrand factor forms and increased platelet aggregation. Measurement of ADAMTS-13 activity is useful for the diagnosis of TTP and may also be relevant as a prognostic test for recurrent TTP. Udgivelsesdato: 2008-Aug-11

M3 - Tidsskriftartikel

C2 - 18761827

SN - 0041-5782

VL - 170

SP - 2446

EP - 2449

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

IS - 33

ER -