Novel understanding of self-reactive T cells

Mads Hald Andersen

doi:10.1080/2162402x.2015.1083672

Novel understanding of self-reactive T cells

Mads Hald Andersen^*

^*Corresponding author for this work

2 Citations (Scopus)

Abstract

In a recent issue of Immunity, Mark Davis and colleagues describe that thymic selection does not eliminate but prunes self-reactive T cell clones. Self-reactive T cells are a natural part of the T-cell repertoire and may be important in the fight against pathogens in addition to being important immune regulators.

Original language	English
Article number	e1083672
Journal	OncoImmunology
Volume	5
Issue number	3
Number of pages	2
ISSN	2162-4011
DOIs	https://doi.org/10.1080/2162402x.2015.1083672
Publication status	Published - Mar 2016

Keywords

Anti-Tregs
CD8
IDO
PD-L1
self-reactive T cells
thymic selection

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10.1080/2162402x.2015.1083672

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title = "Novel understanding of self-reactive T cells",

abstract = "In a recent issue of Immunity, Mark Davis and colleagues describe that thymic selection does not eliminate but prunes self-reactive T cell clones. Self-reactive T cells are a natural part of the T-cell repertoire and may be important in the fight against pathogens in addition to being important immune regulators.",

keywords = "Anti-Tregs, CD8, IDO, PD-L1, self-reactive T cells, thymic selection",

author = "Andersen, {Mads Hald}",

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AB - In a recent issue of Immunity, Mark Davis and colleagues describe that thymic selection does not eliminate but prunes self-reactive T cell clones. Self-reactive T cells are a natural part of the T-cell repertoire and may be important in the fight against pathogens in addition to being important immune regulators.

KW - Anti-Tregs

KW - CD8

KW - IDO

KW - PD-L1

KW - self-reactive T cells

KW - thymic selection

U2 - 10.1080/2162402x.2015.1083672

DO - 10.1080/2162402x.2015.1083672

M3 - Editorial

C2 - 27141338

AN - SCOPUS:84961602248

SN - 2162-4011

VL - 5

JO - OncoImmunology

JF - OncoImmunology

IS - 3

M1 - e1083672

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Novel understanding of self-reactive T cells

Abstract

Keywords

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