NOVEL HYDROXAMIC ACIDS HAVING HISTONE DEACETYLASE INHIBITING ACTIVITY AND ANTI-CANCER COMPOSITION COMPRISING THE SAME AS AN ACTIVE INGREDIENT

Truong Thanh Tung (Inventor), HAN SANG BAE ; KIM YOUNG SOO ; HONG JIN TAE ; NGUYEN HAI NAM ; VAN THI MY HUE ; DAO THI KIM OANH (Inventor)

    Abstract

    The present invention relates to a pharmaceutical composition for anticancer including novel hydroxamic acid with histone deacetylase inhibiting activity as an active ingredient. Hydroxamic acid compound of the present invention has inhibitory activity of histone deacetylase (HDAC) and shows cytotoxicity to a variety of cancer cells, being useful in strong anti-cancer drug.
    Original languageEnglish
    IPCC07D277/44
    Patent numberKR101384350 (B1)
    Filing date14/04/2014
    Country/TerritoryKorea, Republic of
    Priority date21/06/2012
    Priority numberKR20120066831 20120621
    Publication statusPublished - 31 Dec 2013

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