Novel algorithms for the pragmatic use of ultrasound in the management of patients with rheumatoid arthritis: From diagnosis to remission

Maria-Antonietta D'Agostino; Lene Terslev; Richard Wakefield; Mikkel Østergaard; Peter Balint; Esperanza Naredo; Annamaria Iagnocco; Marina Backhaus; Walter Grassi; Paul Emery

doi:10.1136/annrheumdis-2016-209646

Novel algorithms for the pragmatic use of ultrasound in the management of patients with rheumatoid arthritis: From diagnosis to remission

Maria-Antonietta D'Agostino, Lene Terslev, Richard Wakefield, Mikkel Østergaard, Peter Balint, Esperanza Naredo, Annamaria Iagnocco, Marina Backhaus, Walter Grassi, Paul Emery^*

^*Corresponding author for this work

Department of Clinical Medicine

60 Citations (Scopus)

Abstract

The absence of specific guidance on how to use ultrasound (US) to diagnose and manage patients with inflammatory arthritis, especially with rheumatoid arthritis (RA) has hindered the optimal utilisation of US in clinical practice, potentially limiting its benefits for patient outcomes. In view of this, a group of musculoskeletal US experts formed a working group to consider how this unmet need could be satisfied and to produce guidance (additional to European League against Rheumatism (EULAR) imaging recommendations) to support clinicians in their daily clinical work. This paper describes this process and its outcome, namely five novel algorithms, which identify when US could be used. They are designed to aid diagnosis, to inform assessment of treatment response/disease monitoring and to evaluate stable disease state or remission in patients with suspected or established RA, by providing a pragmatic template for using US at certain time points of the RA management. A research agenda has also been defined for answering unmet clinical needs.

Original language	English
Journal	Annals of the Rheumatic Diseases
Volume	75
Issue number	11
Pages (from-to)	1902-1908
Number of pages	7
ISSN	0003-4967
DOIs	https://doi.org/10.1136/annrheumdis-2016-209646
Publication status	Published - 2016

Keywords

Rheumatoid Arthritis
Synovitis
Ultrasonography

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D'Agostino, M-A., Terslev, L., Wakefield, R., Østergaard, M., Balint, P., Naredo, E., Iagnocco, A., Backhaus, M., Grassi, W., & Emery, P. (2016). Novel algorithms for the pragmatic use of ultrasound in the management of patients with rheumatoid arthritis: From diagnosis to remission. Annals of the Rheumatic Diseases, 75(11), 1902-1908. https://doi.org/10.1136/annrheumdis-2016-209646

D'Agostino, M-A, Terslev, L, Wakefield, R, Østergaard, M, Balint, P, Naredo, E, Iagnocco, A, Backhaus, M, Grassi, W & Emery, P 2016, 'Novel algorithms for the pragmatic use of ultrasound in the management of patients with rheumatoid arthritis: From diagnosis to remission', Annals of the Rheumatic Diseases, vol. 75, no. 11, pp. 1902-1908. https://doi.org/10.1136/annrheumdis-2016-209646

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abstract = "The absence of specific guidance on how to use ultrasound (US) to diagnose and manage patients with inflammatory arthritis, especially with rheumatoid arthritis (RA) has hindered the optimal utilisation of US in clinical practice, potentially limiting its benefits for patient outcomes. In view of this, a group of musculoskeletal US experts formed a working group to consider how this unmet need could be satisfied and to produce guidance (additional to European League against Rheumatism (EULAR) imaging recommendations) to support clinicians in their daily clinical work. This paper describes this process and its outcome, namely five novel algorithms, which identify when US could be used. They are designed to aid diagnosis, to inform assessment of treatment response/disease monitoring and to evaluate stable disease state or remission in patients with suspected or established RA, by providing a pragmatic template for using US at certain time points of the RA management. A research agenda has also been defined for answering unmet clinical needs.",

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doi = "10.1136/annrheumdis-2016-209646",

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AU - D'Agostino, Maria-Antonietta

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AU - Wakefield, Richard

AU - Østergaard, Mikkel

AU - Balint, Peter

AU - Naredo, Esperanza

AU - Iagnocco, Annamaria

AU - Backhaus, Marina

AU - Grassi, Walter

AU - Emery, Paul

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AB - The absence of specific guidance on how to use ultrasound (US) to diagnose and manage patients with inflammatory arthritis, especially with rheumatoid arthritis (RA) has hindered the optimal utilisation of US in clinical practice, potentially limiting its benefits for patient outcomes. In view of this, a group of musculoskeletal US experts formed a working group to consider how this unmet need could be satisfied and to produce guidance (additional to European League against Rheumatism (EULAR) imaging recommendations) to support clinicians in their daily clinical work. This paper describes this process and its outcome, namely five novel algorithms, which identify when US could be used. They are designed to aid diagnosis, to inform assessment of treatment response/disease monitoring and to evaluate stable disease state or remission in patients with suspected or established RA, by providing a pragmatic template for using US at certain time points of the RA management. A research agenda has also been defined for answering unmet clinical needs.

KW - Rheumatoid Arthritis

KW - Synovitis

KW - Ultrasonography

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Novel algorithms for the pragmatic use of ultrasound in the management of patients with rheumatoid arthritis: From diagnosis to remission

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Keywords

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