Nitrogen excretion in rats on a protein-free diet and during starvation

André Chwalibog, Ewa Sawosz, Tomasz Niemiec, Marta Grodzik, Grete Thorbek

    1 Citation (Scopus)

    Abstract

    Nitrogen balances (six days) were determined in male Wistar rats during feeding a diet with sufficient protein or a nearly protein-free diet (n = 2 x 24), and then during three days of starvation (n = 2 x 12). The objective was to evaluate the effect of protein withdrawal on minimum nitrogen excretion in urine (UN), corresponding to endogenous UN, during feeding and subsequent starvation periods. The rats fed the protein free-diet had almost the same excretion of urinary N during feeding and starvation (165 and 157 mg/kg W(0.75)), while it was 444 mg/kg W(0.75) in rats previously fed with protein, demonstrating a major influence of protein content in a diet on N excretion during starvation. Consequently, the impact of former protein supply on N losses during starvation ought to be considered when evaluating minimum N requirement necessary to sustain life.
    Original languageEnglish
    JournalArchives of Animal Nutrition
    Volume62
    Issue number1
    Pages (from-to)82-85
    Number of pages4
    ISSN1745-039X
    DOIs
    Publication statusPublished - 2008

    Keywords

    • Animal Nutritional Physiological Phenomena
    • Animals
    • Body Weight
    • Diet, Protein-Restricted
    • Dietary Proteins
    • Digestion
    • Feces
    • Male
    • Nitrogen
    • Nutritional Requirements
    • Rats
    • Rats, Wistar
    • Starvation

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