[New marker in thrombotic thrombocytopenic purpura]

A. Hillarp; A. Lindblom; P. Bjork; K. Strandberg; L.B. Nielsen; Jens Peter Gøtze

[New marker in thrombotic thrombocytopenic purpura]

A. Hillarp, A. Lindblom, P. Bjork, K. Strandberg, L.B. Nielsen, Jens Peter Gøtze

2 Citations (Scopus)

Abstract

Thrombotic microangiopathy can be caused by several conditions which are difficult to diagnose from the clinical presentation alone. Deficient enzyme activity of a newly-discovered enzyme, ADAMTS-13, can lead to thrombotic thrombocytopenic purpura (TTP). Lack of ADAMTS-13 activity causes increased concentrations of high molecular weight von Willebrand factor forms and increased platelet aggregation. Measurement of ADAMTS-13 activity is useful for the diagnosis of TTP and may also be relevant as a prognostic test for recurrent TTP
Udgivelsesdato: 2008/8/11

Original language	Danish
Journal	Ugeskrift for læger
Volume	170
Issue number	33
Pages (from-to)	2446-2449
Number of pages	3
ISSN	0041-5782
Publication status	Published - 2008

Cite this

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title = "[New marker in thrombotic thrombocytopenic purpura]",

abstract = "Thrombotic microangiopathy can be caused by several conditions which are difficult to diagnose from the clinical presentation alone. Deficient enzyme activity of a newly-discovered enzyme, ADAMTS-13, can lead to thrombotic thrombocytopenic purpura (TTP). Lack of ADAMTS-13 activity causes increased concentrations of high molecular weight von Willebrand factor forms and increased platelet aggregation. Measurement of ADAMTS-13 activity is useful for the diagnosis of TTP and may also be relevant as a prognostic test for recurrent TTP Udgivelsesdato: 2008/8/11",

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year = "2008",

language = "Dansk",

volume = "170",

pages = "2446--2449",

journal = "Ugeskrift for Laeger",

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publisher = "Almindelige Danske Laegeforening",

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TY - JOUR

T1 - [New marker in thrombotic thrombocytopenic purpura]

AU - Hillarp, A.

AU - Lindblom, A.

AU - Bjork, P.

AU - Strandberg, K.

AU - Nielsen, L.B.

AU - Gøtze, Jens Peter

PY - 2008

Y1 - 2008

N2 - Thrombotic microangiopathy can be caused by several conditions which are difficult to diagnose from the clinical presentation alone. Deficient enzyme activity of a newly-discovered enzyme, ADAMTS-13, can lead to thrombotic thrombocytopenic purpura (TTP). Lack of ADAMTS-13 activity causes increased concentrations of high molecular weight von Willebrand factor forms and increased platelet aggregation. Measurement of ADAMTS-13 activity is useful for the diagnosis of TTP and may also be relevant as a prognostic test for recurrent TTP Udgivelsesdato: 2008/8/11

AB - Thrombotic microangiopathy can be caused by several conditions which are difficult to diagnose from the clinical presentation alone. Deficient enzyme activity of a newly-discovered enzyme, ADAMTS-13, can lead to thrombotic thrombocytopenic purpura (TTP). Lack of ADAMTS-13 activity causes increased concentrations of high molecular weight von Willebrand factor forms and increased platelet aggregation. Measurement of ADAMTS-13 activity is useful for the diagnosis of TTP and may also be relevant as a prognostic test for recurrent TTP Udgivelsesdato: 2008/8/11

M3 - Tidsskriftartikel

SN - 0041-5782

VL - 170

SP - 2446

EP - 2449

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

IS - 33

ER -