Neuroradiologiske forandringer ved undertrykkelse af tics

Translated title of the contribution: Neuroradiological changes by suppression of tics

Sara Bohn Larsen, Camilla Birgitte Sørensen, Liselotte Skov, Nanette Mol Debes

Abstract

Tourette's syndrome is characterized by involuntary tics. First choice of treatment has been pharmacological, but recently, behavioural therapy teaching patients to suppress their tics has been introduced. Neuroimaging studies have shown an increased activity in the prefrontal cortex, temporal lobes and caudate nucleus, and a decreased activity in globus pallidus and putamen during inhibition of tics. The activity in the frontal lobes changes with age, probably caused by a lack of compensatory hypertrophy. In order to fully understand the mechanism behind behavioural therapy further studies are needed.

Translated title of the contributionNeuroradiological changes by suppression of tics
Original languageDanish
Article numberV06160424
JournalUgeskrift for Laeger
Volume179
Issue number1
Number of pages4
ISSN0041-5782
Publication statusPublished - 2017

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