N-terminal pro-B-type natriuretic peptide in patients with growth hormone disturbances

Mikkel Andreassen; Jens Faber; Henrik Vestergaard; Caroline Kistorp; Lars Østergaard Kristensen

doi:10.1111/j.1365-2265.2007.02782.x

N-terminal pro-B-type natriuretic peptide in patients with growth hormone disturbances

Mikkel Andreassen, Jens Faber, Henrik Vestergaard, Caroline Kistorp, Lars Østergaard Kristensen

Department of Clinical Medicine

15 Citations (Scopus)

Abstract

Acromegaly is associated with hypertrophic cardiomyopathy, hypertension and subsequent congestive heart failure. Impairment of cardiac function has also been associated with growth hormone deficiency (GHD). B-type natriuretic peptides (BNPs) have emerged as strong diagnostic and prognostic risk markers. They are cardioprotective hormones that compensate heart disease by promoting natriuresis and modulation of cardiac hypertrophy in response to volume expansion and ventricular wall stretch.

Original language	English
Journal	Clinical Endocrinology
Volume	66
Issue number	5
Pages (from-to)	619-25
Number of pages	7
ISSN	0300-0664
DOIs	https://doi.org/10.1111/j.1365-2265.2007.02782.x
Publication status	Published - May 2007

Keywords

Acromegaly
Adult
Aged
Analysis of Variance
Antineoplastic Agents, Hormonal
Biological Markers
Case-Control Studies
Female
Follow-Up Studies
Growth Hormone
Humans
Insulin-Like Growth Factor Binding Protein 3
Insulin-Like Growth Factor I
Male
Middle Aged
Natriuretic Peptide, Brain
Octreotide
Peptide Fragments
Peptides, Cyclic
Protein Precursors
Retrospective Studies
Somatostatin
Statistics, Nonparametric

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10.1111/j.1365-2265.2007.02782.x

Cite this

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title = "N-terminal pro-B-type natriuretic peptide in patients with growth hormone disturbances",

abstract = "Acromegaly is associated with hypertrophic cardiomyopathy, hypertension and subsequent congestive heart failure. Impairment of cardiac function has also been associated with growth hormone deficiency (GHD). B-type natriuretic peptides (BNPs) have emerged as strong diagnostic and prognostic risk markers. They are cardioprotective hormones that compensate heart disease by promoting natriuresis and modulation of cardiac hypertrophy in response to volume expansion and ventricular wall stretch.",

keywords = "Acromegaly, Adult, Aged, Analysis of Variance, Antineoplastic Agents, Hormonal, Biological Markers, Case-Control Studies, Female, Follow-Up Studies, Growth Hormone, Humans, Insulin-Like Growth Factor Binding Protein 3, Insulin-Like Growth Factor I, Male, Middle Aged, Natriuretic Peptide, Brain, Octreotide, Peptide Fragments, Peptides, Cyclic, Protein Precursors, Retrospective Studies, Somatostatin, Statistics, Nonparametric",

author = "Mikkel Andreassen and Jens Faber and Henrik Vestergaard and Caroline Kistorp and Kristensen, {Lars {\O}stergaard}",

year = "2007",

month = may,

doi = "10.1111/j.1365-2265.2007.02782.x",

language = "English",

volume = "66",

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T1 - N-terminal pro-B-type natriuretic peptide in patients with growth hormone disturbances

AU - Andreassen, Mikkel

AU - Faber, Jens

AU - Vestergaard, Henrik

AU - Kistorp, Caroline

AU - Kristensen, Lars Østergaard

PY - 2007/5

Y1 - 2007/5

N2 - Acromegaly is associated with hypertrophic cardiomyopathy, hypertension and subsequent congestive heart failure. Impairment of cardiac function has also been associated with growth hormone deficiency (GHD). B-type natriuretic peptides (BNPs) have emerged as strong diagnostic and prognostic risk markers. They are cardioprotective hormones that compensate heart disease by promoting natriuresis and modulation of cardiac hypertrophy in response to volume expansion and ventricular wall stretch.

AB - Acromegaly is associated with hypertrophic cardiomyopathy, hypertension and subsequent congestive heart failure. Impairment of cardiac function has also been associated with growth hormone deficiency (GHD). B-type natriuretic peptides (BNPs) have emerged as strong diagnostic and prognostic risk markers. They are cardioprotective hormones that compensate heart disease by promoting natriuresis and modulation of cardiac hypertrophy in response to volume expansion and ventricular wall stretch.

KW - Acromegaly

KW - Adult

KW - Aged

KW - Analysis of Variance

KW - Antineoplastic Agents, Hormonal

KW - Biological Markers

KW - Case-Control Studies

KW - Female

KW - Follow-Up Studies

KW - Growth Hormone

KW - Humans

KW - Insulin-Like Growth Factor Binding Protein 3

KW - Insulin-Like Growth Factor I

KW - Male

KW - Middle Aged

KW - Natriuretic Peptide, Brain

KW - Octreotide

KW - Peptide Fragments

KW - Peptides, Cyclic

KW - Protein Precursors

KW - Retrospective Studies

KW - Somatostatin

KW - Statistics, Nonparametric

U2 - 10.1111/j.1365-2265.2007.02782.x

DO - 10.1111/j.1365-2265.2007.02782.x

M3 - Journal article

C2 - 17492947

SN - 0300-0664

VL - 66

SP - 619

EP - 625

JO - Clinical Endocrinology

JF - Clinical Endocrinology

IS - 5

ER -

N-terminal pro-B-type natriuretic peptide in patients with growth hormone disturbances

Abstract

Keywords

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