Myeloid sarcoma developing in pre-existing pyoderma gangrenosum

Ida Bruun Kristensen; Hanne Møller; Mette Wanscher Kjaerskov; Knud Yderstraede; Michael Boe Møller; Olav J Bergmann

doi:10.2340/00015555-0590

Myeloid sarcoma developing in pre-existing pyoderma gangrenosum

Ida Bruun Kristensen, Hanne Møller, Mette Wanscher Kjaerskov, Knud Yderstraede, Michael Boe Møller, Olav J Bergmann

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4 Citations (Scopus)

Abstract

We report here a case of pyoderma gangrenosum in a patient with myelodysplastic syndrome developing into myeloid sarcoma as a sign of transformation to acute leukaemia. The patient was treated successfully with intensive chemotherapy and achieved complete remission, and her otherwise expanding ulcers started to heal. This is the first reported case of secondary blastic infiltration in pyoderma gangrenosum, and it underlines the importance of performing re-biopsy of non-healing ulcers, especially in patients with an underlying haematological disease.

Original language	English
Journal	Acta Dermato Venereologica
Volume	89
Issue number	2
Pages (from-to)	175-7
Number of pages	2
ISSN	0001-5555
DOIs	https://doi.org/10.2340/00015555-0590
Publication status	Published - 2009

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title = "Myeloid sarcoma developing in pre-existing pyoderma gangrenosum",

abstract = "We report here a case of pyoderma gangrenosum in a patient with myelodysplastic syndrome developing into myeloid sarcoma as a sign of transformation to acute leukaemia. The patient was treated successfully with intensive chemotherapy and achieved complete remission, and her otherwise expanding ulcers started to heal. This is the first reported case of secondary blastic infiltration in pyoderma gangrenosum, and it underlines the importance of performing re-biopsy of non-healing ulcers, especially in patients with an underlying haematological disease.",

author = "Kristensen, {Ida Bruun} and Hanne M{\o}ller and Kjaerskov, {Mette Wanscher} and Knud Yderstraede and M{\o}ller, {Michael Boe} and Bergmann, {Olav J}",

note = "Keywords: Cell Transformation, Neoplastic; Female; Humans; Leg Ulcer; Leukemia, Myeloid, Acute; Middle Aged; Myelodysplastic Syndromes; Pyoderma Gangrenosum; Sarcoma, Myeloid; Skin Neoplasms",

year = "2009",

doi = "10.2340/00015555-0590",

language = "English",

volume = "89",

pages = "175--7",

journal = "Acta Dermato-Venereologica",

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T1 - Myeloid sarcoma developing in pre-existing pyoderma gangrenosum

AU - Kristensen, Ida Bruun

AU - Møller, Hanne

AU - Kjaerskov, Mette Wanscher

AU - Yderstraede, Knud

AU - Møller, Michael Boe

AU - Bergmann, Olav J

N1 - Keywords: Cell Transformation, Neoplastic; Female; Humans; Leg Ulcer; Leukemia, Myeloid, Acute; Middle Aged; Myelodysplastic Syndromes; Pyoderma Gangrenosum; Sarcoma, Myeloid; Skin Neoplasms

PY - 2009

Y1 - 2009

N2 - We report here a case of pyoderma gangrenosum in a patient with myelodysplastic syndrome developing into myeloid sarcoma as a sign of transformation to acute leukaemia. The patient was treated successfully with intensive chemotherapy and achieved complete remission, and her otherwise expanding ulcers started to heal. This is the first reported case of secondary blastic infiltration in pyoderma gangrenosum, and it underlines the importance of performing re-biopsy of non-healing ulcers, especially in patients with an underlying haematological disease.

AB - We report here a case of pyoderma gangrenosum in a patient with myelodysplastic syndrome developing into myeloid sarcoma as a sign of transformation to acute leukaemia. The patient was treated successfully with intensive chemotherapy and achieved complete remission, and her otherwise expanding ulcers started to heal. This is the first reported case of secondary blastic infiltration in pyoderma gangrenosum, and it underlines the importance of performing re-biopsy of non-healing ulcers, especially in patients with an underlying haematological disease.

U2 - 10.2340/00015555-0590

DO - 10.2340/00015555-0590

M3 - Journal article

C2 - 19326005

SN - 0001-5555

VL - 89

SP - 175

EP - 177

JO - Acta Dermato-Venereologica

JF - Acta Dermato-Venereologica

IS - 2

ER -

Myeloid sarcoma developing in pre-existing pyoderma gangrenosum

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