Mutational analysis of the UCP2 core promoter and relationships of variants with obesity

Louise T Dalgaard, Gitte Andersen, Lesli H Larsen, Thorkild I A Sørensen, Teis Andersen, Thomas Drivsholm, Knut Borch-Johnsen, Jan Fleckner, Torben Hansen, Nanni Din, Oluf Pedersen

41 Citations (Scopus)

Abstract

To identify polymorphisms in the human uncoupling protein 2 gene (UCP2) promoter and to investigate whether these were associated with obesity or weight gain.
Original languageEnglish
JournalObesity Research
Volume11
Issue number11
Pages (from-to)1420-7
Number of pages8
ISSN1071-7323
DOIs
Publication statusPublished - 1 Nov 2003

Keywords

  • Adipose Tissue
  • Adult
  • Aged
  • Aged, 80 and over
  • Animals
  • Cell Line
  • DNA Mutational Analysis
  • Denmark
  • Embryo, Mammalian
  • Female
  • Genes, Reporter
  • Genotype
  • Humans
  • Ion Channels
  • Kidney
  • Male
  • Membrane Transport Proteins
  • Mice
  • Middle Aged
  • Mitochondrial Proteins
  • Muscle, Skeletal
  • Mutation
  • Obesity
  • Phenotype
  • Polymorphism, Genetic
  • Promoter Regions, Genetic

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