Mutation analysis of peroxisome proliferator-activated receptor-gamma coactivator-1 (PGC-1) and relationships of identified amino acid polymorphisms to Type II diabetes mellitus

J Ek, G Andersen, S A Urhammer, P H Gaede, T Drivsholm, K Borch-Johnsen, T Hansen, O Pedersen

263 Citations (Scopus)

Abstract

This study aimed to investigate if variability in the peroxisome proliferator-activated receptor-gamma coactivator-1 (PGC-1) gene is associated with Type II (non-insulin-dependent) diabetes mellitus.
Original languageEnglish
JournalDiabetologia
Volume44
Issue number12
Pages (from-to)2220-6
Number of pages7
ISSN0012-186X
DOIs
Publication statusPublished - 1 Dec 2001

Keywords

  • Aged
  • Alleles
  • Amino Acid Sequence
  • DNA Mutational Analysis
  • Diabetes Mellitus, Type 2
  • Female
  • Gene Frequency
  • Genetic Predisposition to Disease
  • Genotype
  • Humans
  • Male
  • Middle Aged
  • Polymorphism, Genetic
  • Transcription Factors

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