Multinucleated spermatogonia in cryptorchid boys: a possible association with an increased risk of testicular malignancy later in life?

Dina Cortes; Jørgen Thorup; Jakob Visfeldt

Multinucleated spermatogonia in cryptorchid boys: a possible association with an increased risk of testicular malignancy later in life?

Dina Cortes, Jørgen Thorup, Jakob Visfeldt

Department of Clinical Medicine

30 Citations (Scopus)

Abstract

At birth, undescended testes contain germ cells, but after 1 year of life, a reduced number of germ cells is generally found. Microlithiasis and carcinoma-in-situ-testis occur in cryptorchid boys. Multinucleated germ cells, including at least 3 nuclei in the cell, exist in impaired spermatogenesis and in the senescent testis.

Original language	English
Journal	Acta Pathologica Microbiologica et Immunologica Scandinavica
Volume	111
Issue number	1
Pages (from-to)	25-30; discussion 31
ISSN	0903-4641
Publication status	Published - 1 Jan 2003

Keywords

Biopsy
Carcinoma in Situ
Cell Nucleus
Child
Child, Preschool
Cryptorchidism
Erythropoietin
Humans
Infant
Male
Precancerous Conditions
Renal Insufficiency
Risk Factors
Spermatogonia
Testicular Neoplasms

Cite this

Multinucleated spermatogonia in cryptorchid boys: a possible association with an increased risk of testicular malignancy later in life? / Cortes, Dina ; Thorup, Jørgen; Visfeldt, Jakob.

In: Acta Pathologica Microbiologica et Immunologica Scandinavica, Vol. 111, No. 1, 01.01.2003, p. 25-30; discussion 31.

Research output: Contribution to journal › Journal article › Research › peer-review

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title = "Multinucleated spermatogonia in cryptorchid boys: a possible association with an increased risk of testicular malignancy later in life?",

abstract = "At birth, undescended testes contain germ cells, but after 1 year of life, a reduced number of germ cells is generally found. Microlithiasis and carcinoma-in-situ-testis occur in cryptorchid boys. Multinucleated germ cells, including at least 3 nuclei in the cell, exist in impaired spermatogenesis and in the senescent testis.",

keywords = "Biopsy, Carcinoma in Situ, Cell Nucleus, Child, Child, Preschool, Cryptorchidism, Erythropoietin, Humans, Infant, Male, Precancerous Conditions, Renal Insufficiency, Risk Factors, Spermatogonia, Testicular Neoplasms",

author = "Dina Cortes and J{\o}rgen Thorup and Jakob Visfeldt",

year = "2003",

month = jan,

day = "1",

language = "English",

volume = "111",

pages = "25--30; discussion 31",

journal = "APMIS. Supplementum",

issn = "0903-465X",