[Multi-facetted clinical presentation of thrombotic thrombocytopenic purpura]

C.U. Niemann; J. Jurlander; G. Daugaard; L. Friis-Hansen

[Multi-facetted clinical presentation of thrombotic thrombocytopenic purpura]

C.U. Niemann, J. Jurlander, G. Daugaard, L. Friis-Hansen

Department of Clinical Medicine

Abstract

Thrombotic thrombocytopenic purpura (TTP) is a thrombotic microangiopathic disease. TTP is due to reduced activity of the von Willebrand factor which cleaves ADAMTS13. The disease is characterized by thrombocytopenia (<20 billion/l) intravascular Coombs-negative haemolysis and schistocytes in blood smears. Determination of the ADAMTS13-activity is now becoming available as a routine analysis. We present two cases that illustrate the multi-facetted clinical presentation under which TTP occurs. The importance of access to ADAMTS13 measurements is stressed
Udgivelsesdato: 2009/1/26

Original language	Danish
Journal	Ugeskrift for læger
Volume	171
Issue number	5
Pages (from-to)	340-342
Number of pages	2
ISSN	0041-5782
Publication status	Published - 2009

Cite this

@article{31232b70626d11df928f000ea68e967b,

title = "[Multi-facetted clinical presentation of thrombotic thrombocytopenic purpura]",

abstract = "Thrombotic thrombocytopenic purpura (TTP) is a thrombotic microangiopathic disease. TTP is due to reduced activity of the von Willebrand factor which cleaves ADAMTS13. The disease is characterized by thrombocytopenia (<20 billion/l) intravascular Coombs-negative haemolysis and schistocytes in blood smears. Determination of the ADAMTS13-activity is now becoming available as a routine analysis. We present two cases that illustrate the multi-facetted clinical presentation under which TTP occurs. The importance of access to ADAMTS13 measurements is stressed Udgivelsesdato: 2009/1/26",

author = "C.U. Niemann and J. Jurlander and G. Daugaard and L. Friis-Hansen",

note = "Cochrane: Den danske tekst er klippet hertil ,Trombotisk purpuras mange ansigter, og den eng. downloadet fra PubMed.",

year = "2009",

language = "Dansk",

volume = "171",

pages = "340--342",

journal = "Ugeskrift for Laeger",

issn = "0041-5782",

publisher = "Almindelige Danske Laegeforening",

number = "5",

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TY - JOUR

T1 - [Multi-facetted clinical presentation of thrombotic thrombocytopenic purpura]

AU - Niemann, C.U.

AU - Jurlander, J.

AU - Daugaard, G.

AU - Friis-Hansen, L.

N1 - Cochrane: Den danske tekst er klippet hertil ,Trombotisk purpuras mange ansigter, og den eng. downloadet fra PubMed.

PY - 2009

Y1 - 2009

N2 - Thrombotic thrombocytopenic purpura (TTP) is a thrombotic microangiopathic disease. TTP is due to reduced activity of the von Willebrand factor which cleaves ADAMTS13. The disease is characterized by thrombocytopenia (<20 billion/l) intravascular Coombs-negative haemolysis and schistocytes in blood smears. Determination of the ADAMTS13-activity is now becoming available as a routine analysis. We present two cases that illustrate the multi-facetted clinical presentation under which TTP occurs. The importance of access to ADAMTS13 measurements is stressed Udgivelsesdato: 2009/1/26

AB - Thrombotic thrombocytopenic purpura (TTP) is a thrombotic microangiopathic disease. TTP is due to reduced activity of the von Willebrand factor which cleaves ADAMTS13. The disease is characterized by thrombocytopenia (<20 billion/l) intravascular Coombs-negative haemolysis and schistocytes in blood smears. Determination of the ADAMTS13-activity is now becoming available as a routine analysis. We present two cases that illustrate the multi-facetted clinical presentation under which TTP occurs. The importance of access to ADAMTS13 measurements is stressed Udgivelsesdato: 2009/1/26

M3 - Tidsskriftartikel

SN - 0041-5782

VL - 171

SP - 340

EP - 342

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

IS - 5

ER -