Abstract
BACKGROUND AND PURPOSE: In the world today 10-20 million people are still living with late effects of poliomyelitis (PM), but the long-term consequences of the disease are not well known. The aim of this study was to describe lifelong morbidity and mortality among Danes who survived PM.
METHODS: Data from official registers for a cohort of 3606 Danes hospitalized for PM in the period 1940-1954 were compared with 13 762 age- and gender-matched controls.
RESULTS: Compared with controls, mortality was moderately increased for both paralytic as well as non-paralytic PM cases; Hazard Ratio, 1.31 (95% confidence interval, 1.18-1.44) and 1.09 (95% confidence interval, 1.00-1.19), respectively. Hospitalization rates were approximately 1.5 times higher among both paralytic and non-paralytic PM cases as compared with controls. Discharge diagnoses showed a broad spectrum of diseases. There were no major differences in morbidities between paralytic and non-paralytic PM cases.
CONCLUSIONS: Poliomyelitis has significant long-term consequences on morbidity and mortality of both paralytic and non-paralytic cases.
| Original language | English |
|---|---|
| Journal | European Journal of Neurology |
| Volume | 24 |
| Issue number | 2 |
| Pages (from-to) | 326-333 |
| ISSN | 1351-5101 |
| DOIs | |
| Publication status | Published - 1 Feb 2017 |
Keywords
- Age Factors
- Aged
- Aged, 80 and over
- Denmark/epidemiology
- Female
- Follow-Up Studies
- Hospitalization/statistics & numerical data
- Humans
- Kaplan-Meier Estimate
- Male
- Middle Aged
- Paralysis/complications
- Poliomyelitis/epidemiology
