Molekylaer patogenese ved monogen og polygen fedme

Philip J Larsen; Søren Morgenthaler Echwald; Thorkild I A Sørensen; Oluf Borbye Pedersen

Molekylaer patogenese ved monogen og polygen fedme

Translated title of the contribution: Molecular pathogenesis in monogenic and polygenic obesity

Philip J Larsen, Søren Morgenthaler Echwald, Thorkild I A Sørensen, Oluf Borbye Pedersen

1 Citation (Scopus)

Abstract

During the last few years, studies of the molecular pathogenesis of obesity both in mouse models and in the rare cases of monogenic obesity in humans have added significantly to our understanding of the key role of the hypothalamus in mediating hunger and satiety. These insights have brought us closer to the development of rational therapies of obesity, the epidemic of which is continuing in the post-industrial society, which is characterised by sedentary behaviour patterns.

Translated title of the contribution	Molecular pathogenesis in monogenic and polygenic obesity
Original language	Danish
Journal	Ugeskrift for Laeger
Volume	168
Issue number	2
Pages (from-to)	152-5
Number of pages	4
ISSN	0041-5782
Publication status	Published - 2006

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title = "Molekylaer patogenese ved monogen og polygen fedme",

abstract = "During the last few years, studies of the molecular pathogenesis of obesity both in mouse models and in the rare cases of monogenic obesity in humans have added significantly to our understanding of the key role of the hypothalamus in mediating hunger and satiety. These insights have brought us closer to the development of rational therapies of obesity, the epidemic of which is continuing in the post-industrial society, which is characterised by sedentary behaviour patterns.",

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T1 - Molekylaer patogenese ved monogen og polygen fedme

AU - Larsen, Philip J

AU - Echwald, Søren Morgenthaler

AU - Sørensen, Thorkild I A

AU - Pedersen, Oluf Borbye

PY - 2006

Y1 - 2006

N2 - During the last few years, studies of the molecular pathogenesis of obesity both in mouse models and in the rare cases of monogenic obesity in humans have added significantly to our understanding of the key role of the hypothalamus in mediating hunger and satiety. These insights have brought us closer to the development of rational therapies of obesity, the epidemic of which is continuing in the post-industrial society, which is characterised by sedentary behaviour patterns.

AB - During the last few years, studies of the molecular pathogenesis of obesity both in mouse models and in the rare cases of monogenic obesity in humans have added significantly to our understanding of the key role of the hypothalamus in mediating hunger and satiety. These insights have brought us closer to the development of rational therapies of obesity, the epidemic of which is continuing in the post-industrial society, which is characterised by sedentary behaviour patterns.

KW - Animals

KW - Appetite

KW - Humans

KW - Hypothalamus

KW - Mice

KW - Obesity

KW - Receptors, Cell Surface

KW - Receptors, Leptin

KW - Satiation

M3 - Tidsskriftartikel

C2 - 16403339

SN - 0041-5782

VL - 168

SP - 152

EP - 155

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

IS - 2

ER -

Molekylaer patogenese ved monogen og polygen fedme

Abstract

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