Mitochondrial Plasticity With Exercise Training and Extreme Environments

TY - JOUR

T1 - Mitochondrial Plasticity With Exercise Training and Extreme Environments

AU - Boushel, Robert

AU - Lundby, Carsten

AU - Qvortrup, Klaus

AU - Sahlin, Kent

PY - 2014/10

Y1 - 2014/10

N2 - Mitochondria form a reticulum in skeletal muscle. Exercise training stimulates mitochondrial biogenesis, yet an emerging hypothesis is that training also induces qualitative regulatory changes. Substrate oxidation, oxygen affinity, and biochemical coupling efficiency may be regulated differentially with training and exposure to extreme environments. Threshold training doses inducing mitochondrial upregulation remain to be elucidated considering fitness level.

AB - Mitochondria form a reticulum in skeletal muscle. Exercise training stimulates mitochondrial biogenesis, yet an emerging hypothesis is that training also induces qualitative regulatory changes. Substrate oxidation, oxygen affinity, and biochemical coupling efficiency may be regulated differentially with training and exposure to extreme environments. Threshold training doses inducing mitochondrial upregulation remain to be elucidated considering fitness level.

U2 - 10.1249/jes.0000000000000025

DO - 10.1249/jes.0000000000000025

M3 - Journal article

C2 - 25062000

SN - 0091-6331

VL - 42

SP - 169

EP - 174

JO - Exercise and Sport Sciences Reviews

JF - Exercise and Sport Sciences Reviews

IS - 4

ER -