Mitochondrial haplogroups: ischemic cardiovascular disease, other diseases, mortality, and longevity in the general population

Marianne Benn, Marianne Schwartz, Børge G Nordestgaard, Anne Tybjaerg-Hansen

    51 Citations (Scopus)

    Abstract

    Rare mutations in the mitochondrial genome may cause disease. Mitochondrial haplogroups defined by common polymorphisms have been associated with risk of disease and longevity. We tested the hypothesis that common haplogroups predict risk of ischemic cardiovascular disease, morbidity from other causes, mortality, and longevity in a general population of European descent.
    Original languageEnglish
    JournalCirculation
    Volume117
    Issue number19
    Pages (from-to)2492-501
    Number of pages10
    ISSN0009-7322
    DOIs
    Publication statusPublished - 2008

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