Minipig negative slow wave demonstrates target/nontarget differences in P300 paradigm

Sidse Marie Arnfred; Nanna Marie Lind; Anette Moustgaard; Axel Kornerup Hansen; Albert Gjedde

Minipig negative slow wave demonstrates target/nontarget differences in P300 paradigm

Sidse Marie Arnfred, Nanna Marie Lind, Anette Moustgaard, Axel Kornerup Hansen, Albert Gjedde

7 Citations (Scopus)

Abstract

The negative slow wave (NSW) is a late component of the event-related potential (ERP) in man modulated like the P300 by the stimulus, the task, and the response demand. Aiming at the development of a minipig model of schizophrenia, we investigated scalp ERPs in an auditory P300 paradigm in six Göttingen minipigs. Before training, we observed no difference between target and nontarget NSW. After training, target NSW amplitude was increased 50% compared to nontarget. A P350 was recognized, but the finding of a lack of target/nontarget difference is not conclusive.

Original language	English
Journal	NeuroImage
Volume	20
Issue number	1
Pages (from-to)	587-90
Number of pages	3
ISSN	1053-8119
Publication status	Published - 2003
Externally published	Yes

Cite this

@article{3f37a4f0b31511debc73000ea68e967b,

title = "Minipig negative slow wave demonstrates target/nontarget differences in P300 paradigm",

abstract = "The negative slow wave (NSW) is a late component of the event-related potential (ERP) in man modulated like the P300 by the stimulus, the task, and the response demand. Aiming at the development of a minipig model of schizophrenia, we investigated scalp ERPs in an auditory P300 paradigm in six G{\"o}ttingen minipigs. Before training, we observed no difference between target and nontarget NSW. After training, target NSW amplitude was increased 50% compared to nontarget. A P350 was recognized, but the finding of a lack of target/nontarget difference is not conclusive.",

author = "Arnfred, {Sidse Marie} and Lind, {Nanna Marie} and Anette Moustgaard and Hansen, {Axel Kornerup} and Albert Gjedde",

year = "2003",

language = "English",

volume = "20",

pages = "587--90",

journal = "NeuroImage",

issn = "1053-8119",

publisher = "Elsevier",

number = "1",

}

TY - JOUR

T1 - Minipig negative slow wave demonstrates target/nontarget differences in P300 paradigm

AU - Arnfred, Sidse Marie

AU - Lind, Nanna Marie

AU - Moustgaard, Anette

AU - Hansen, Axel Kornerup

AU - Gjedde, Albert

PY - 2003

Y1 - 2003

N2 - The negative slow wave (NSW) is a late component of the event-related potential (ERP) in man modulated like the P300 by the stimulus, the task, and the response demand. Aiming at the development of a minipig model of schizophrenia, we investigated scalp ERPs in an auditory P300 paradigm in six Göttingen minipigs. Before training, we observed no difference between target and nontarget NSW. After training, target NSW amplitude was increased 50% compared to nontarget. A P350 was recognized, but the finding of a lack of target/nontarget difference is not conclusive.

AB - The negative slow wave (NSW) is a late component of the event-related potential (ERP) in man modulated like the P300 by the stimulus, the task, and the response demand. Aiming at the development of a minipig model of schizophrenia, we investigated scalp ERPs in an auditory P300 paradigm in six Göttingen minipigs. Before training, we observed no difference between target and nontarget NSW. After training, target NSW amplitude was increased 50% compared to nontarget. A P350 was recognized, but the finding of a lack of target/nontarget difference is not conclusive.

M3 - Journal article

C2 - 14527619

SN - 1053-8119

VL - 20

SP - 587

EP - 590

JO - NeuroImage

JF - NeuroImage

IS - 1

ER -

Minipig negative slow wave demonstrates target/nontarget differences in P300 paradigm

Abstract

Fingerprint

Cite this