Mineralization of the metre-long biosilica structures of glass sponges is templated on hydroxylated collagen

Hermann Ehrlich; Rainer Deutzmann; Eike Brunner; Enrico Cappellini; Hannah Koon; Caroline Solazzo; Yue Yang; David Ashford; Jane Thomas-Oates; Markus Lubeck; Carsten Baessmann; Tobias Langrock; Ralf Hoffmann; Gert Wörheide; Joachim Reitner; Paul Simon; Mikhail Tsurkan; Aleksander V. Ereskovsky; Denis Kurek; Vasily V. Bazhenov; Sebastian Hunoldt; Michael Mertig; Denis V. Vyalikh; Serguei L. Molodtsov; Kurt Kummer; Hartmut Worch; Victor Smetacek; Matthew J. Collins

doi:10.1038/nchem.899

Mineralization of the metre-long biosilica structures of glass sponges is templated on hydroxylated collagen

Hermann Ehrlich, Rainer Deutzmann, Eike Brunner, Enrico Cappellini, Hannah Koon, Caroline Solazzo, Yue Yang, David Ashford, Jane Thomas-Oates, Markus Lubeck, Carsten Baessmann, Tobias Langrock, Ralf Hoffmann, Gert Wörheide, Joachim Reitner, Paul Simon, Mikhail Tsurkan, Aleksander V. Ereskovsky, Denis Kurek, Vasily V. BazhenovSebastian Hunoldt, Michael Mertig, Denis V. Vyalikh, Serguei L. Molodtsov, Kurt Kummer, Hartmut Worch, Victor Smetacek, Matthew J. Collins

112 Citations (Scopus)

Abstract

The minerals involved in the formation of metazoan skeletons principally comprise glassy silica, calcium phosphate or carbonate. Because of their ancient heritage, glass sponges (Hexactinellida) may shed light on fundamental questions such as molecular evolution, the unique chemistry and formation of the first skeletal silica-based structures, and the origin of multicellular animals. We have studied anchoring spicules from the metre-long stalk of the glass rope sponge (Hyalonema sieboldi; Porifera, Class Hexactinellida), which are remarkable for their size, durability, flexibility and optical properties. Using slow-alkali etching of biosilica, we isolated the organic fraction, which was revealed to be dominated by a hydroxylated fibrillar collagen that contains an unusual [Gly-3Hyp-4Hyp] motif. We speculate that this motif is predisposed for silica precipitation, and provides a novel template for biosilicification in nature.

Original language	English
Journal	Nature Chemistry
Volume	2
Issue number	12
Pages (from-to)	1084-1088
Number of pages	5
ISSN	1755-4330
DOIs	https://doi.org/10.1038/nchem.899
Publication status	Published - Dec 2010
Externally published	Yes

Keywords

Amino Acid Motifs
Amino Acid Sequence
Animals
Collagen
Evolution, Molecular
Hydroxylation
Nanoparticles
Porifera
Silicon Dioxide

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Ehrlich, H., Deutzmann, R., Brunner, E., Cappellini, E., Koon, H., Solazzo, C., Yang, Y., Ashford, D., Thomas-Oates, J., Lubeck, M., Baessmann, C., Langrock, T., Hoffmann, R., Wörheide, G., Reitner, J., Simon, P., Tsurkan, M., Ereskovsky, A. V., Kurek, D., ... Collins, M. J. (2010). Mineralization of the metre-long biosilica structures of glass sponges is templated on hydroxylated collagen. Nature Chemistry, 2(12), 1084-1088. https://doi.org/10.1038/nchem.899

Ehrlich, H, Deutzmann, R, Brunner, E, Cappellini, E, Koon, H, Solazzo, C, Yang, Y, Ashford, D, Thomas-Oates, J, Lubeck, M, Baessmann, C, Langrock, T, Hoffmann, R, Wörheide, G, Reitner, J, Simon, P, Tsurkan, M, Ereskovsky, AV, Kurek, D, Bazhenov, VV, Hunoldt, S, Mertig, M, Vyalikh, DV, Molodtsov, SL, Kummer, K, Worch, H, Smetacek, V & Collins, MJ 2010, 'Mineralization of the metre-long biosilica structures of glass sponges is templated on hydroxylated collagen', Nature Chemistry, vol. 2, no. 12, pp. 1084-1088. https://doi.org/10.1038/nchem.899

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abstract = "The minerals involved in the formation of metazoan skeletons principally comprise glassy silica, calcium phosphate or carbonate. Because of their ancient heritage, glass sponges (Hexactinellida) may shed light on fundamental questions such as molecular evolution, the unique chemistry and formation of the first skeletal silica-based structures, and the origin of multicellular animals. We have studied anchoring spicules from the metre-long stalk of the glass rope sponge (Hyalonema sieboldi; Porifera, Class Hexactinellida), which are remarkable for their size, durability, flexibility and optical properties. Using slow-alkali etching of biosilica, we isolated the organic fraction, which was revealed to be dominated by a hydroxylated fibrillar collagen that contains an unusual [Gly-3Hyp-4Hyp] motif. We speculate that this motif is predisposed for silica precipitation, and provides a novel template for biosilicification in nature.",

keywords = "Amino Acid Motifs, Amino Acid Sequence, Animals, Collagen, Evolution, Molecular, Hydroxylation, Nanoparticles, Porifera, Silicon Dioxide",

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AU - Cappellini, Enrico

AU - Koon, Hannah

AU - Solazzo, Caroline

AU - Yang, Yue

AU - Ashford, David

AU - Thomas-Oates, Jane

AU - Lubeck, Markus

AU - Baessmann, Carsten

AU - Langrock, Tobias

AU - Hoffmann, Ralf

AU - Wörheide, Gert

AU - Reitner, Joachim

AU - Simon, Paul

AU - Tsurkan, Mikhail

AU - Ereskovsky, Aleksander V.

AU - Kurek, Denis

AU - Bazhenov, Vasily V.

AU - Hunoldt, Sebastian

AU - Mertig, Michael

AU - Vyalikh, Denis V.

AU - Molodtsov, Serguei L.

AU - Kummer, Kurt

AU - Worch, Hartmut

AU - Smetacek, Victor

AU - Collins, Matthew J.

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N2 - The minerals involved in the formation of metazoan skeletons principally comprise glassy silica, calcium phosphate or carbonate. Because of their ancient heritage, glass sponges (Hexactinellida) may shed light on fundamental questions such as molecular evolution, the unique chemistry and formation of the first skeletal silica-based structures, and the origin of multicellular animals. We have studied anchoring spicules from the metre-long stalk of the glass rope sponge (Hyalonema sieboldi; Porifera, Class Hexactinellida), which are remarkable for their size, durability, flexibility and optical properties. Using slow-alkali etching of biosilica, we isolated the organic fraction, which was revealed to be dominated by a hydroxylated fibrillar collagen that contains an unusual [Gly-3Hyp-4Hyp] motif. We speculate that this motif is predisposed for silica precipitation, and provides a novel template for biosilicification in nature.

AB - The minerals involved in the formation of metazoan skeletons principally comprise glassy silica, calcium phosphate or carbonate. Because of their ancient heritage, glass sponges (Hexactinellida) may shed light on fundamental questions such as molecular evolution, the unique chemistry and formation of the first skeletal silica-based structures, and the origin of multicellular animals. We have studied anchoring spicules from the metre-long stalk of the glass rope sponge (Hyalonema sieboldi; Porifera, Class Hexactinellida), which are remarkable for their size, durability, flexibility and optical properties. Using slow-alkali etching of biosilica, we isolated the organic fraction, which was revealed to be dominated by a hydroxylated fibrillar collagen that contains an unusual [Gly-3Hyp-4Hyp] motif. We speculate that this motif is predisposed for silica precipitation, and provides a novel template for biosilicification in nature.

KW - Amino Acid Motifs

KW - Amino Acid Sequence

KW - Animals

KW - Collagen

KW - Evolution, Molecular

KW - Hydroxylation

KW - Nanoparticles

KW - Porifera

KW - Silicon Dioxide

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DO - 10.1038/nchem.899

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JO - Nature Chemistry

JF - Nature Chemistry

IS - 12

ER -

Mineralization of the metre-long biosilica structures of glass sponges is templated on hydroxylated collagen

Abstract

Keywords

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