Miljøepidemiologisk forskning fører til saenkning af graensevaerdien for kviksølv

Pál Weihe; Froôi Debes; Roberta F White; Nicolina Sørensen; Esben Budtz-Jørgensen; Niels Keiding; Philippe Grandjean

Miljøepidemiologisk forskning fører til saenkning af graensevaerdien for kviksølv

Translated title of the contribution: Environmental epidemiology research leads to a decrease of the exposure limit for mercury

Pál Weihe, Froôi Debes, Roberta F White, Nicolina Sørensen, Esben Budtz-Jørgensen, Niels Keiding, Philippe Grandjean

8 Citations (Scopus)

Abstract

The central nervous system is particularly vulnerable to prenatal exposure to methylmercury. Due to the widespread exposure to methylmercury from fish, several prospective environmental epidemiology studies have been initiated, in which the maternal exposure during the pregnancy is related to the neurobehavioural development of the children. We have studied a Faroese birth cohort prenatally exposed to methylmercury from maternal intake of contaminated pilot whale meat. At seven years of age, clear dose-response relationships were observed for deficits in attention, language, and memory. An increase in blood pressure was also associated with the prenatal exposure level. The exposure limit for mercury has therefore been decreased.
Udgivelsesdato: 2003-Jan-6

Translated title of the contribution	Environmental epidemiology research leads to a decrease of the exposure limit for mercury
Original language	Danish
Journal	Ugeskrift for læger
Volume	165
Issue number	2
Pages (from-to)	107-11
Number of pages	4
ISSN	0041-5782
Publication status	Published - 2003

Cite this

@article{b2a9e0809eaa11debc73000ea68e967b,

title = "Milj{\o}epidemiologisk forskning f{\o}rer til saenkning af graensevaerdien for kviks{\o}lv",

abstract = "The central nervous system is particularly vulnerable to prenatal exposure to methylmercury. Due to the widespread exposure to methylmercury from fish, several prospective environmental epidemiology studies have been initiated, in which the maternal exposure during the pregnancy is related to the neurobehavioural development of the children. We have studied a Faroese birth cohort prenatally exposed to methylmercury from maternal intake of contaminated pilot whale meat. At seven years of age, clear dose-response relationships were observed for deficits in attention, language, and memory. An increase in blood pressure was also associated with the prenatal exposure level. The exposure limit for mercury has therefore been decreased. Udgivelsesdato: 2003-Jan-6",

author = "P{\'a}l Weihe and Fro{\^o}i Debes and White, {Roberta F} and Nicolina S{\o}rensen and Esben Budtz-J{\o}rgensen and Niels Keiding and Philippe Grandjean",

note = "Keywords: Animals; Attention Deficit Disorder with Hyperactivity; Child; Cohort Studies; Developmental Disabilities; Dolphins; Dose-Response Relationship, Drug; Environmental Exposure; Female; Fishes; Food Contamination; Humans; Hypertension; Language Disorders; Maximum Allowable Concentration; Memory Disorders; Methylmercury Compounds; Pregnancy; Prenatal Exposure Delayed Effects; Prospective Studies; Research",

year = "2003",

language = "Dansk",

volume = "165",

pages = "107--11",

journal = "Ugeskrift for Laeger",

issn = "0041-5782",

publisher = "Almindelige Danske Laegeforening",

number = "2",

}

TY - JOUR

T1 - Miljøepidemiologisk forskning fører til saenkning af graensevaerdien for kviksølv

AU - Weihe, Pál

AU - Debes, Froôi

AU - White, Roberta F

AU - Sørensen, Nicolina

AU - Budtz-Jørgensen, Esben

AU - Keiding, Niels

AU - Grandjean, Philippe

N1 - Keywords: Animals; Attention Deficit Disorder with Hyperactivity; Child; Cohort Studies; Developmental Disabilities; Dolphins; Dose-Response Relationship, Drug; Environmental Exposure; Female; Fishes; Food Contamination; Humans; Hypertension; Language Disorders; Maximum Allowable Concentration; Memory Disorders; Methylmercury Compounds; Pregnancy; Prenatal Exposure Delayed Effects; Prospective Studies; Research

PY - 2003

Y1 - 2003

N2 - The central nervous system is particularly vulnerable to prenatal exposure to methylmercury. Due to the widespread exposure to methylmercury from fish, several prospective environmental epidemiology studies have been initiated, in which the maternal exposure during the pregnancy is related to the neurobehavioural development of the children. We have studied a Faroese birth cohort prenatally exposed to methylmercury from maternal intake of contaminated pilot whale meat. At seven years of age, clear dose-response relationships were observed for deficits in attention, language, and memory. An increase in blood pressure was also associated with the prenatal exposure level. The exposure limit for mercury has therefore been decreased. Udgivelsesdato: 2003-Jan-6

AB - The central nervous system is particularly vulnerable to prenatal exposure to methylmercury. Due to the widespread exposure to methylmercury from fish, several prospective environmental epidemiology studies have been initiated, in which the maternal exposure during the pregnancy is related to the neurobehavioural development of the children. We have studied a Faroese birth cohort prenatally exposed to methylmercury from maternal intake of contaminated pilot whale meat. At seven years of age, clear dose-response relationships were observed for deficits in attention, language, and memory. An increase in blood pressure was also associated with the prenatal exposure level. The exposure limit for mercury has therefore been decreased. Udgivelsesdato: 2003-Jan-6

M3 - Tidsskriftartikel

C2 - 12561779

SN - 0041-5782

VL - 165

SP - 107

EP - 111

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

IS - 2

ER -