MicroRNAs and gene regulatory networks: managing the impact of noise in biological systems

Héctor Herranz; Stephen M Cohen

doi:10.1101/gad.1937010

MicroRNAs and gene regulatory networks: managing the impact of noise in biological systems

281 Citations (Scopus)

Abstract

Biological systems are continuously challenged by an environment that is variable. Yet, a key feature of developmental and physiological processes is their remarkable stability. This review considers how microRNAs contribute to gene regulatory networks that confer robustness.

Original language	English
Journal	Genes & Development
Volume	24
Issue number	13
Pages (from-to)	1339-44
Number of pages	6
ISSN	0890-9369
DOIs	https://doi.org/10.1101/gad.1937010
Publication status	Published - 1 Jul 2010
Externally published	Yes

Keywords

Animals
Cell Differentiation
Epithelial Cells
Feedback, Physiological
Gene Regulatory Networks
Genes, Switch
Humans
MicroRNAs
Neurons
Protein Interaction Domains and Motifs

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10.1101/gad.1937010

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title = "MicroRNAs and gene regulatory networks: managing the impact of noise in biological systems",

abstract = "Biological systems are continuously challenged by an environment that is variable. Yet, a key feature of developmental and physiological processes is their remarkable stability. This review considers how microRNAs contribute to gene regulatory networks that confer robustness.",

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AU - Cohen, Stephen M

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AB - Biological systems are continuously challenged by an environment that is variable. Yet, a key feature of developmental and physiological processes is their remarkable stability. This review considers how microRNAs contribute to gene regulatory networks that confer robustness.

KW - Animals

KW - Cell Differentiation

KW - Epithelial Cells

KW - Feedback, Physiological

KW - Gene Regulatory Networks

KW - Genes, Switch

KW - Humans

KW - MicroRNAs

KW - Neurons

KW - Protein Interaction Domains and Motifs

U2 - 10.1101/gad.1937010

DO - 10.1101/gad.1937010

M3 - Journal article

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JO - Genes & Development

JF - Genes & Development

IS - 13

ER -

MicroRNAs and gene regulatory networks: managing the impact of noise in biological systems

Abstract

Keywords

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