Metastasis-inducing S100A4 protein is associated with the disease activity of rheumatoid arthritis

Lucie Oslejsková; Mariam Grigorian; Hana Hulejová; Jirí Vencovsky; Karel Pavelka; Jörg Klingelhöfer; Steffen Gay; Michel Neidhart; Hana Brabcová; David Suchy; Ladislav Senolt

doi:10.1093/rheumatology/kep316

Metastasis-inducing S100A4 protein is associated with the disease activity of rheumatoid arthritis

Lucie Oslejsková, Mariam Grigorian, Hana Hulejová, Jirí Vencovsky, Karel Pavelka, Jörg Klingelhöfer, Steffen Gay, Michel Neidhart, Hana Brabcová, David Suchy, Ladislav Senolt

33 Citations (Scopus)

Abstract

To evaluate the association between metastasis-inducing protein S100A4 and disease activity in patients with RA, and to demonstrate the effect of TNF-alpha blocking therapy on plasma levels of S100A4 in these patients.

Original language	English
Journal	Rheumatology (Online)
Volume	48
Issue number	12
Pages (from-to)	1590-4
Number of pages	5
ISSN	1462-0332
DOIs	https://doi.org/10.1093/rheumatology/kep316
Publication status	Published - Dec 2009

Keywords

Adult
Antibodies, Monoclonal
Antibodies, Monoclonal, Humanized
Antirheumatic Agents
Arthritis, Rheumatoid
Biological Markers
Cells, Cultured
Female
Humans
Male
Middle Aged
Monocytes
RNA, Messenger
Reverse Transcriptase Polymerase Chain Reaction
S100 Proteins
Severity of Illness Index
Tumor Necrosis Factor-alpha
Up-Regulation

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title = "Metastasis-inducing S100A4 protein is associated with the disease activity of rheumatoid arthritis",

abstract = "To evaluate the association between metastasis-inducing protein S100A4 and disease activity in patients with RA, and to demonstrate the effect of TNF-alpha blocking therapy on plasma levels of S100A4 in these patients.",

keywords = "Adult, Antibodies, Monoclonal, Antibodies, Monoclonal, Humanized, Antirheumatic Agents, Arthritis, Rheumatoid, Biological Markers, Cells, Cultured, Female, Humans, Male, Middle Aged, Monocytes, RNA, Messenger, Reverse Transcriptase Polymerase Chain Reaction, S100 Proteins, Severity of Illness Index, Tumor Necrosis Factor-alpha, Up-Regulation",

author = "Lucie Oslejskov{\'a} and Mariam Grigorian and Hana Hulejov{\'a} and Jir{\'i} Vencovsky and Karel Pavelka and J{\"o}rg Klingelh{\"o}fer and Steffen Gay and Michel Neidhart and Hana Brabcov{\'a} and David Suchy and Ladislav Senolt",

year = "2009",

month = dec,

doi = "10.1093/rheumatology/kep316",

language = "English",

volume = "48",

pages = "1590--4",

journal = "Rheumatology",

issn = "1462-0324",

publisher = "Oxford University Press",

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TY - JOUR

T1 - Metastasis-inducing S100A4 protein is associated with the disease activity of rheumatoid arthritis

AU - Oslejsková, Lucie

AU - Grigorian, Mariam

AU - Hulejová, Hana

AU - Vencovsky, Jirí

AU - Pavelka, Karel

AU - Klingelhöfer, Jörg

AU - Gay, Steffen

AU - Neidhart, Michel

AU - Brabcová, Hana

AU - Suchy, David

AU - Senolt, Ladislav

PY - 2009/12

Y1 - 2009/12

N2 - To evaluate the association between metastasis-inducing protein S100A4 and disease activity in patients with RA, and to demonstrate the effect of TNF-alpha blocking therapy on plasma levels of S100A4 in these patients.

AB - To evaluate the association between metastasis-inducing protein S100A4 and disease activity in patients with RA, and to demonstrate the effect of TNF-alpha blocking therapy on plasma levels of S100A4 in these patients.

KW - Adult

KW - Antibodies, Monoclonal

KW - Antibodies, Monoclonal, Humanized

KW - Antirheumatic Agents

KW - Arthritis, Rheumatoid

KW - Biological Markers

KW - Cells, Cultured

KW - Female

KW - Humans

KW - Male

KW - Middle Aged

KW - Monocytes

KW - RNA, Messenger

KW - Reverse Transcriptase Polymerase Chain Reaction

KW - S100 Proteins

KW - Severity of Illness Index

KW - Tumor Necrosis Factor-alpha

KW - Up-Regulation

U2 - 10.1093/rheumatology/kep316

DO - 10.1093/rheumatology/kep316

M3 - Journal article

C2 - 19828600

SN - 1462-0324

VL - 48

SP - 1590

EP - 1594

JO - Rheumatology

JF - Rheumatology

IS - 12

ER -

Metastasis-inducing S100A4 protein is associated with the disease activity of rheumatoid arthritis

Abstract

Keywords

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