Metabolomics kan potentielt forbedre lægemiddelterapien

Claus Stage; Gesche Jürgens; Kim Peder Dalhoff; Henrik Berg Rasmussen

Metabolomics kan potentielt forbedre lægemiddelterapien

Translated title of the contribution: Metabolomics has the potential to improve drug therapy.

Claus Stage, Gesche Jürgens, Kim Peder Dalhoff, Henrik Berg Rasmussen

Department of Clinical Medicine

Abstract

Until now drug therapy has primarily been controlled by dose titration on the basis of effects and side effects. However, a lot of people being treated with a drug experience too little effect or too many side effects. Therefore it will be advantageous to improve drug therapy and make it even more "individualized". In this chase metabolomics is a hot topic. The aim of this paper is to review the concepts of metabolomics and the possible applications in regard to drug development, drug therapy and diagnosis, prognosis and monitoring of diseases.

Translated title of the contribution	Metabolomics has the potential to improve drug therapy.
Original language	Danish
Article number	V02130127
Journal	Ugeskrift for Laeger
Volume	176
Issue number	6
Pages (from-to)	525-528
Number of pages	4
ISSN	0041-5782
Publication status	Published - 17 Mar 2014

Cite this

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AU - Stage, Claus

AU - Jürgens, Gesche

AU - Dalhoff, Kim Peder

AU - Rasmussen, Henrik Berg

PY - 2014/3/17

Y1 - 2014/3/17

N2 - Until now drug therapy has primarily been controlled by dose titration on the basis of effects and side effects. However, a lot of people being treated with a drug experience too little effect or too many side effects. Therefore it will be advantageous to improve drug therapy and make it even more "individualized". In this chase metabolomics is a hot topic. The aim of this paper is to review the concepts of metabolomics and the possible applications in regard to drug development, drug therapy and diagnosis, prognosis and monitoring of diseases.

AB - Until now drug therapy has primarily been controlled by dose titration on the basis of effects and side effects. However, a lot of people being treated with a drug experience too little effect or too many side effects. Therefore it will be advantageous to improve drug therapy and make it even more "individualized". In this chase metabolomics is a hot topic. The aim of this paper is to review the concepts of metabolomics and the possible applications in regard to drug development, drug therapy and diagnosis, prognosis and monitoring of diseases.

M3 - Tidsskriftartikel

C2 - 25096206

SN - 0041-5782

VL - 176

SP - 525

EP - 528

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

IS - 6

M1 - V02130127

ER -

Metabolomics kan potentielt forbedre lægemiddelterapien

Abstract

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