Massive fetomaternal hemorrhage caused by an intraplacental choriocarcinoma: a case report

Anna-Karina Aaris Henningsen, Lisa Leth Maroun, Hanne Havsteen, Jens Svare

10 Citations (Scopus)

Abstract

Background. Intraplacental choriocarcinoma is a rare but highly malignant trophoblastic neoplasm. When found near term the risk of maternal metastasis is high because of the late diagnosis. Case. We describe a case of an intraplacental choriocarcinoma diagnosed postpartum after a near-term delivery of a severely anemic infant. A fetomaternal hemorrhage resulted in a hemoglobin concentration in the infant of only 2,1 g/dL. Neither mother nor child showed signs of metastatic disease. The macroscopic examination showed a hydropic placenta weighing more than 1 kilogram. Microscopy showed an intraplacental choriocarcinoma 3 cm in diameter. The tumor had infiltrated the maternal basal plate. Conclusion. Fetomaternal bleeding is a rare form of presentation of choriocarcinoma but its presence should always warrant detailed examination of placenta, mother, and infant.
Original languageEnglish
JournalCase Reports in Medicine
Volume2010
Number of pages3
DOIs
Publication statusPublished - 1 Jan 2010

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