Abstract
This article provides an overview of clinical aspects of hand eczema in patients with atopic dermatitis. Hand eczema can be a part of atopic dermatitis itself or a comorbidity, for example, as irritant or allergic contact dermatitis. When managing hand eczema, it is important to first categorize the subtype and identify potential culprit allergens or irritants. First-line therapy should be a combination of emollients and topical corticosteroids; possible alternatives include topical calcineurin inhibitors or coal tar. Second-line therapy includes UV therapy and systemic therapy, including azathioprine, cyclosporine, methotrexate, and mycophenolate. Prednisolone should only be very infrequently used.
| Original language | English |
|---|---|
| Journal | Dermatologic Clinics |
| Volume | 35 |
| Issue number | 3 |
| Pages (from-to) | 365-372 |
| ISSN | 0733-8635 |
| DOIs | |
| Publication status | Published - Jul 2017 |
Keywords
- Administration, Cutaneous
- Adrenal Cortex Hormones/therapeutic use
- Anti-Bacterial Agents/therapeutic use
- Calcineurin Inhibitors/therapeutic use
- Coal Tar/therapeutic use
- Comorbidity
- Dermatitis, Atopic/epidemiology
- Dermatologic Agents/therapeutic use
- Eczema/classification
- Emollients/therapeutic use
- Hand Dermatoses/classification
- Humans
- Skin Physiological Phenomena
- Ultraviolet Therapy