Magnetisk resonans og multipel sklerose. II. Nye diagnostiske metoder.

Henrik Kahr Mathiesen; Annika Reynberg Langkilde; Henrik B W Larsson

Magnetisk resonans og multipel sklerose. II. Nye diagnostiske metoder.

Translated title of the contribution: [Magnetic resonance and multiple sclerosis II. New diagnostic techniques]

Henrik Kahr Mathiesen, Annika Reynberg Langkilde, Henrik B W Larsson

3 Citations (Scopus)

Abstract

Conventional magnetic resonance imaging (MRI) techniques have proved important in the diagnosis and in the follow-up in clinical trials of patients with multiple sclerosis (MS). However, these techniques have low specificity for the pathological changes in the MS lesions, and the correlation between conventional MRI and the disability is poor. The last ten years have seen the development of new techniques with improved sensitivity and increased pathological specificity, such as magnetisation transfer imaging (MTI), magnetic resonance spectroscopy (MRS), diffusion-weighted imaging, and functional magnetic resonance imaging (fMRI). These techniques and their contribution to the knowledge about the pathophysiology of MS are described in this review.

Translated title of the contribution	[Magnetic resonance and multiple sclerosis II. New diagnostic techniques]
Original language	Danish
Journal	Ugeskrift for Laeger
Volume	164
Issue number	8
Pages (from-to)	1031-1036
Number of pages	6
ISSN	0041-5782
Publication status	Published - 2002

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Cite this

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title = "Magnetisk resonans og multipel sklerose. II. Nye diagnostiske metoder.",

abstract = "Conventional magnetic resonance imaging (MRI) techniques have proved important in the diagnosis and in the follow-up in clinical trials of patients with multiple sclerosis (MS). However, these techniques have low specificity for the pathological changes in the MS lesions, and the correlation between conventional MRI and the disability is poor. The last ten years have seen the development of new techniques with improved sensitivity and increased pathological specificity, such as magnetisation transfer imaging (MTI), magnetic resonance spectroscopy (MRS), diffusion-weighted imaging, and functional magnetic resonance imaging (fMRI). These techniques and their contribution to the knowledge about the pathophysiology of MS are described in this review.",

author = "Mathiesen, {Henrik Kahr} and Langkilde, {Annika Reynberg} and Larsson, {Henrik B W}",

year = "2002",

language = "Dansk",

volume = "164",

pages = "1031--1036",

journal = "Ugeskrift for Laeger",

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T1 - Magnetisk resonans og multipel sklerose. II. Nye diagnostiske metoder.

AU - Mathiesen, Henrik Kahr

AU - Langkilde, Annika Reynberg

AU - Larsson, Henrik B W

PY - 2002

Y1 - 2002

N2 - Conventional magnetic resonance imaging (MRI) techniques have proved important in the diagnosis and in the follow-up in clinical trials of patients with multiple sclerosis (MS). However, these techniques have low specificity for the pathological changes in the MS lesions, and the correlation between conventional MRI and the disability is poor. The last ten years have seen the development of new techniques with improved sensitivity and increased pathological specificity, such as magnetisation transfer imaging (MTI), magnetic resonance spectroscopy (MRS), diffusion-weighted imaging, and functional magnetic resonance imaging (fMRI). These techniques and their contribution to the knowledge about the pathophysiology of MS are described in this review.

AB - Conventional magnetic resonance imaging (MRI) techniques have proved important in the diagnosis and in the follow-up in clinical trials of patients with multiple sclerosis (MS). However, these techniques have low specificity for the pathological changes in the MS lesions, and the correlation between conventional MRI and the disability is poor. The last ten years have seen the development of new techniques with improved sensitivity and increased pathological specificity, such as magnetisation transfer imaging (MTI), magnetic resonance spectroscopy (MRS), diffusion-weighted imaging, and functional magnetic resonance imaging (fMRI). These techniques and their contribution to the knowledge about the pathophysiology of MS are described in this review.

M3 - Review

SN - 0041-5782

VL - 164

SP - 1031

EP - 1036

JO - Ugeskrift for Laeger

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