Magnetic field associated with spreading depression: a model for the detection of migraine

Yoshio C. Okada; Martin Lauritzen; Charles Nicholson

doi:10.1016/0006-8993(88)91450-3

Magnetic field associated with spreading depression: a model for the detection of migraine

Yoshio C. Okada^*, Martin Lauritzen, Charles Nicholson

^*Corresponding author for this work

Neuronal Signalling

43 Citations (Scopus)

Abstract

Slow variations of the magnetic field were recorded in real time during spreading depression (SD) in the isolated turtle cerebellum. The magnetic signal lasted for 2-10 min with the largest amplitude in the first minute. The field strength was of sufficient magnitude to be measured unaveraged at 2-4 cm from the tissue. The directions and time course of the magnetic signal indicated that cerebellar SD is accompanied by current normal to the cerebellar surface. The observations reported here are of clinical interest due to the potential involvement of SD in various neurological disorders, notably head trauma and migraine.

Original language	English
Journal	Brain Research
Volume	442
Issue number	1
Pages (from-to)	185-190
Number of pages	6
ISSN	0006-8993
DOIs	https://doi.org/10.1016/0006-8993(88)91450-3
Publication status	Published - 23 Feb 1988

Keywords

Biomagnetism
Cerebellum
Evoked magnetic field
Migraine
Spreading depression

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10.1016/0006-8993(88)91450-3

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abstract = "Slow variations of the magnetic field were recorded in real time during spreading depression (SD) in the isolated turtle cerebellum. The magnetic signal lasted for 2-10 min with the largest amplitude in the first minute. The field strength was of sufficient magnitude to be measured unaveraged at 2-4 cm from the tissue. The directions and time course of the magnetic signal indicated that cerebellar SD is accompanied by current normal to the cerebellar surface. The observations reported here are of clinical interest due to the potential involvement of SD in various neurological disorders, notably head trauma and migraine.",

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T2 - a model for the detection of migraine

AU - Okada, Yoshio C.

AU - Lauritzen, Martin

AU - Nicholson, Charles

PY - 1988/2/23

Y1 - 1988/2/23

N2 - Slow variations of the magnetic field were recorded in real time during spreading depression (SD) in the isolated turtle cerebellum. The magnetic signal lasted for 2-10 min with the largest amplitude in the first minute. The field strength was of sufficient magnitude to be measured unaveraged at 2-4 cm from the tissue. The directions and time course of the magnetic signal indicated that cerebellar SD is accompanied by current normal to the cerebellar surface. The observations reported here are of clinical interest due to the potential involvement of SD in various neurological disorders, notably head trauma and migraine.

AB - Slow variations of the magnetic field were recorded in real time during spreading depression (SD) in the isolated turtle cerebellum. The magnetic signal lasted for 2-10 min with the largest amplitude in the first minute. The field strength was of sufficient magnitude to be measured unaveraged at 2-4 cm from the tissue. The directions and time course of the magnetic signal indicated that cerebellar SD is accompanied by current normal to the cerebellar surface. The observations reported here are of clinical interest due to the potential involvement of SD in various neurological disorders, notably head trauma and migraine.

KW - Biomagnetism

KW - Cerebellum

KW - Evoked magnetic field

KW - Migraine

KW - Spreading depression

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Magnetic field associated with spreading depression: a model for the detection of migraine

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Keywords

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