Lung cancer screening with low dose CT requires careful consideration

Zaigham Saghir; Haseem Ashraf; Karen Skjøldstrup Bach; John Brodersen; Paul Frost Clementsen; Martin Døssing; Hanne Hansen; Klaus Fuglsang Kofoed; Klaus Richter Larsen; Jann Mortensen; Jakob Fraes Rasmussen; Laura Hohwü Thomsen; Mathilde Marie Winkler Wille; Niels Seersholm; Birgit Guldhammer Skov; Hanne Thorsen; Philip Tønnesen; Jesper Holst Pedersen

Lung cancer screening with low dose CT requires careful consideration

Zaigham Saghir, Haseem Ashraf, Karen Skjøldstrup Bach, John Brodersen, Paul Frost Clementsen, Martin Døssing, Hanne Hansen, Klaus Fuglsang Kofoed, Klaus Richter Larsen, Jann Mortensen, Jakob Fraes Rasmussen, Laura Hohwü Thomsen, Mathilde Marie Winkler Wille, Niels Seersholm, Birgit Guldhammer Skov, Hanne Thorsen, Philip Tønnesen, Jesper Holst Pedersen

1 Citation (Scopus)

Abstract

Results from the American National Lung Screening Trial (NLST) show a significant reduction in lung cancer and all-cause mortality in a high risk population screened with annual low-dose CT. Handling of pulmonary nodules, false positive tests, overdiagnosis, psychosocial consequences and cost-efficiency etc. are all aspects that require careful consideration. This paper gives an overview of the current knowledge on these issues. Before a recommendation can be made, we need an overall evaluation of both the benefits and harms in CT screening for lung cancer.

Original language	English
Journal	Ugeskrift for Laeger
Volume	176
Issue number	42
ISSN	0041-5782
Publication status	Published - 13 Oct 2014

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Saghir, Z., Ashraf, H., Bach, K. S., Brodersen, J., Clementsen, P. F., Døssing, M., Hansen, H., Kofoed, K. F., Larsen, K. R., Mortensen, J., Rasmussen, J. F., Thomsen, L. H., Wille, M. M. W., Seersholm, N., Skov, B. G., Thorsen, H., Tønnesen, P., & Pedersen, J. H. (2014). Lung cancer screening with low dose CT requires careful consideration. Ugeskrift for Laeger, 176(42).

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abstract = "Results from the American National Lung Screening Trial (NLST) show a significant reduction in lung cancer and all-cause mortality in a high risk population screened with annual low-dose CT. Handling of pulmonary nodules, false positive tests, overdiagnosis, psychosocial consequences and cost-efficiency etc. are all aspects that require careful consideration. This paper gives an overview of the current knowledge on these issues. Before a recommendation can be made, we need an overall evaluation of both the benefits and harms in CT screening for lung cancer. ",

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AU - Saghir, Zaigham

AU - Ashraf, Haseem

AU - Bach, Karen Skjøldstrup

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AU - Clementsen, Paul Frost

AU - Døssing, Martin

AU - Hansen, Hanne

AU - Kofoed, Klaus Fuglsang

AU - Larsen, Klaus Richter

AU - Mortensen, Jann

AU - Rasmussen, Jakob Fraes

AU - Thomsen, Laura Hohwü

AU - Wille, Mathilde Marie Winkler

AU - Seersholm, Niels

AU - Skov, Birgit Guldhammer

AU - Thorsen, Hanne

AU - Tønnesen, Philip

AU - Pedersen, Jesper Holst

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AB - Results from the American National Lung Screening Trial (NLST) show a significant reduction in lung cancer and all-cause mortality in a high risk population screened with annual low-dose CT. Handling of pulmonary nodules, false positive tests, overdiagnosis, psychosocial consequences and cost-efficiency etc. are all aspects that require careful consideration. This paper gives an overview of the current knowledge on these issues. Before a recommendation can be made, we need an overall evaluation of both the benefits and harms in CT screening for lung cancer.

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Lung cancer screening with low dose CT requires careful consideration

Abstract

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