Abstract
The health-promoting benefits of exercise have been recognized for centuries, yet the molecular and cellular mechanisms for the acute and chronic adaptive response to a variety of physical activities remain incompletely described. This Perspective will take a forward view to highlight emerging questions and frontiers in the ever-changing landscape of exercise biology. The biology of exercise is complex, highly variable, and involves a myriad of adaptive responses in multiple organ systems. Given the multitude of changes that occur in each organ during exercise, future researchers will need to integrate tissue-specific responses with large-scale omics to resolve the integrated biology of exercise. The ultimate goal will be to understand how these system-wide, tissue-specific exercise-induced changes lead to measurable physiological outcomes at the whole-body level to improve health and well-being.
| Original language | English |
|---|---|
| Journal | Cell Metabolism |
| Volume | 22 |
| Issue number | 1 |
| Pages (from-to) | 25-30 |
| Number of pages | 6 |
| ISSN | 1550-4131 |
| DOIs | |
| Publication status | Published - 7 Jul 2015 |