Longitudinal changes in patient-reported outcome measures following total hip arthroplasty and predictors of deterioration during follow-up: a seven-year prospective international multicentre study

V P Galea; P Rojanasopondist; L H Ingelsrud; H E Rubash; C Bragdon; J I Huddleston Iii; H Malchau; A Troelsen

doi:10.1302/0301-620X.101B7.BJJ-2018-1491.R1

Longitudinal changes in patient-reported outcome measures following total hip arthroplasty and predictors of deterioration during follow-up: a seven-year prospective international multicentre study

V P Galea, P Rojanasopondist, L H Ingelsrud, H E Rubash, C Bragdon, J I Huddleston Iii, H Malchau, A Troelsen

Department of Clinical Medicine

6 Citations (Scopus)

Abstract

Aims The primary aim of this study was to quantify the improvement in patient-reported outcome measures (PROMs) following total hip arthroplasty (THA), as well as the extent of any deterioration through the seven-year follow-up. The secondary aim was to identify predictors of PROM improvement and deterioration. Patients and Methods A total of 976 patients were enrolled into a prospective, international, multicentre study. Patients completed a battery of PROMs prior to THA, at three months post-THA, and at one, three, five, and seven-years post-THA. The Harris Hip Score (HHS), the 36-Item Short-Form Health Survey (SF-36) Physical Component Summary (PCS), the SF-36 Mental Component Summary (MCS), and the EuroQol five-dimension three-level (EQ-5D) index were the primary outcomes. Longitudinal changes in each PROM were investigated by piece-wise linear mixed effects models. Clinically significant deterioration was defined for each patient as a decrease of one half of a standard deviation (group baseline). Results Improvements were noted in each PROM between the preoperative and one-year visits, with one-year values exceeding age-matched population norms. Patients with difficulty in self-care experienced less improvement in HHS (odds ratio (OR) 2.2; p = 0.003). Those with anxiety/depression experienced less improvement in PCS (OR -3.3; p = 0.002) and EQ-5D (OR -0.07; p = 0.005). Between one and seven years, obesity was associated with deterioration in HHS (1.5 points/year; p = 0.006), PCS (0.8 points/year; p < 0.001), and EQ-5D (0.02 points/year; p < 0.001). Preoperative difficulty in self-care was associated with deterioration in HHS (2.2 points/year; p < 0.001). Preoperative pain from other joints was associated with deterioration in MCS (0.8 points/year; p < 0.001). All aforementioned factors were associated with clinically significant deterioration in PROMs (p < 0.035), except anxiety/depression with regard to PCS (p = 0.060). Conclusion The present study finds that patient factors affect the improvement and deterioration in PROMs over the medium term following THA. Special attention should be given to patients with risk factors for decreased PROMs, both preoperatively and during follow-up.

Original language	English
Journal	The Bone & Joint Journal
Volume	101-B
Issue number	7
Pages (from-to)	768-778
ISSN	0301-620X
DOIs	https://doi.org/10.1302/0301-620X.101B7.BJJ-2018-1491.R1
Publication status	Published - 2019

Keywords

Adult
Aged
Arthroplasty, Replacement, Hip
Female
Follow-Up Studies
Humans
Male
Middle Aged
Osteoarthritis, Hip/physiopathology
Patient Reported Outcome Measures
Prospective Studies
Prosthesis Failure/etiology
Treatment Outcome

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1302/0301-620X.101B7.BJJ-2018-1491.R1

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Galea, V. P., Rojanasopondist, P., Ingelsrud, L. H., Rubash, H. E., Bragdon, C., Huddleston Iii, J. I., Malchau, H., & Troelsen, A. (2019). Longitudinal changes in patient-reported outcome measures following total hip arthroplasty and predictors of deterioration during follow-up: a seven-year prospective international multicentre study. The Bone & Joint Journal, 101-B(7), 768-778. https://doi.org/10.1302/0301-620X.101B7.BJJ-2018-1491.R1

Longitudinal changes in patient-reported outcome measures following total hip arthroplasty and predictors of deterioration during follow-up : a seven-year prospective international multicentre study. / Galea, V P; Rojanasopondist, P; Ingelsrud, L H et al.

In: The Bone & Joint Journal, Vol. 101-B, No. 7, 2019, p. 768-778.

Research output: Contribution to journal › Journal article › Research › peer-review

Galea, VP, Rojanasopondist, P, Ingelsrud, LH, Rubash, HE, Bragdon, C, Huddleston Iii, JI, Malchau, H & Troelsen, A 2019, 'Longitudinal changes in patient-reported outcome measures following total hip arthroplasty and predictors of deterioration during follow-up: a seven-year prospective international multicentre study', The Bone & Joint Journal, vol. 101-B, no. 7, pp. 768-778. https://doi.org/10.1302/0301-620X.101B7.BJJ-2018-1491.R1

Galea VP, Rojanasopondist P, Ingelsrud LH, Rubash HE, Bragdon C, Huddleston Iii JI et al. Longitudinal changes in patient-reported outcome measures following total hip arthroplasty and predictors of deterioration during follow-up: a seven-year prospective international multicentre study. The Bone & Joint Journal. 2019;101-B(7):768-778. doi: 10.1302/0301-620X.101B7.BJJ-2018-1491.R1

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title = "Longitudinal changes in patient-reported outcome measures following total hip arthroplasty and predictors of deterioration during follow-up: a seven-year prospective international multicentre study",

abstract = "Aims The primary aim of this study was to quantify the improvement in patient-reported outcome measures (PROMs) following total hip arthroplasty (THA), as well as the extent of any deterioration through the seven-year follow-up. The secondary aim was to identify predictors of PROM improvement and deterioration. Patients and Methods A total of 976 patients were enrolled into a prospective, international, multicentre study. Patients completed a battery of PROMs prior to THA, at three months post-THA, and at one, three, five, and seven-years post-THA. The Harris Hip Score (HHS), the 36-Item Short-Form Health Survey (SF-36) Physical Component Summary (PCS), the SF-36 Mental Component Summary (MCS), and the EuroQol five-dimension three-level (EQ-5D) index were the primary outcomes. Longitudinal changes in each PROM were investigated by piece-wise linear mixed effects models. Clinically significant deterioration was defined for each patient as a decrease of one half of a standard deviation (group baseline). Results Improvements were noted in each PROM between the preoperative and one-year visits, with one-year values exceeding age-matched population norms. Patients with difficulty in self-care experienced less improvement in HHS (odds ratio (OR) 2.2; p = 0.003). Those with anxiety/depression experienced less improvement in PCS (OR -3.3; p = 0.002) and EQ-5D (OR -0.07; p = 0.005). Between one and seven years, obesity was associated with deterioration in HHS (1.5 points/year; p = 0.006), PCS (0.8 points/year; p < 0.001), and EQ-5D (0.02 points/year; p < 0.001). Preoperative difficulty in self-care was associated with deterioration in HHS (2.2 points/year; p < 0.001). Preoperative pain from other joints was associated with deterioration in MCS (0.8 points/year; p < 0.001). All aforementioned factors were associated with clinically significant deterioration in PROMs (p < 0.035), except anxiety/depression with regard to PCS (p = 0.060). Conclusion The present study finds that patient factors affect the improvement and deterioration in PROMs over the medium term following THA. Special attention should be given to patients with risk factors for decreased PROMs, both preoperatively and during follow-up.",

keywords = "Adult, Aged, Arthroplasty, Replacement, Hip, Female, Follow-Up Studies, Humans, Male, Middle Aged, Osteoarthritis, Hip/physiopathology, Patient Reported Outcome Measures, Prospective Studies, Prosthesis Failure/etiology, Treatment Outcome",

author = "Galea, {V P} and P Rojanasopondist and Ingelsrud, {L H} and Rubash, {H E} and C Bragdon and {Huddleston Iii}, {J I} and H Malchau and A Troelsen",

year = "2019",

doi = "10.1302/0301-620X.101B7.BJJ-2018-1491.R1",

language = "English",

volume = "101-B",

pages = "768--778",

journal = "Journal of Bone and Joint Surgery: British Volume",

issn = "2049-4394",

publisher = "British Editorial Society of Bone and Joint Surgery",

number = "7",

}

TY - JOUR

T1 - Longitudinal changes in patient-reported outcome measures following total hip arthroplasty and predictors of deterioration during follow-up

T2 - a seven-year prospective international multicentre study

AU - Galea, V P

AU - Rojanasopondist, P

AU - Ingelsrud, L H

AU - Rubash, H E

AU - Bragdon, C

AU - Huddleston Iii, J I

AU - Malchau, H

AU - Troelsen, A

PY - 2019

Y1 - 2019

N2 - Aims The primary aim of this study was to quantify the improvement in patient-reported outcome measures (PROMs) following total hip arthroplasty (THA), as well as the extent of any deterioration through the seven-year follow-up. The secondary aim was to identify predictors of PROM improvement and deterioration. Patients and Methods A total of 976 patients were enrolled into a prospective, international, multicentre study. Patients completed a battery of PROMs prior to THA, at three months post-THA, and at one, three, five, and seven-years post-THA. The Harris Hip Score (HHS), the 36-Item Short-Form Health Survey (SF-36) Physical Component Summary (PCS), the SF-36 Mental Component Summary (MCS), and the EuroQol five-dimension three-level (EQ-5D) index were the primary outcomes. Longitudinal changes in each PROM were investigated by piece-wise linear mixed effects models. Clinically significant deterioration was defined for each patient as a decrease of one half of a standard deviation (group baseline). Results Improvements were noted in each PROM between the preoperative and one-year visits, with one-year values exceeding age-matched population norms. Patients with difficulty in self-care experienced less improvement in HHS (odds ratio (OR) 2.2; p = 0.003). Those with anxiety/depression experienced less improvement in PCS (OR -3.3; p = 0.002) and EQ-5D (OR -0.07; p = 0.005). Between one and seven years, obesity was associated with deterioration in HHS (1.5 points/year; p = 0.006), PCS (0.8 points/year; p < 0.001), and EQ-5D (0.02 points/year; p < 0.001). Preoperative difficulty in self-care was associated with deterioration in HHS (2.2 points/year; p < 0.001). Preoperative pain from other joints was associated with deterioration in MCS (0.8 points/year; p < 0.001). All aforementioned factors were associated with clinically significant deterioration in PROMs (p < 0.035), except anxiety/depression with regard to PCS (p = 0.060). Conclusion The present study finds that patient factors affect the improvement and deterioration in PROMs over the medium term following THA. Special attention should be given to patients with risk factors for decreased PROMs, both preoperatively and during follow-up.

AB - Aims The primary aim of this study was to quantify the improvement in patient-reported outcome measures (PROMs) following total hip arthroplasty (THA), as well as the extent of any deterioration through the seven-year follow-up. The secondary aim was to identify predictors of PROM improvement and deterioration. Patients and Methods A total of 976 patients were enrolled into a prospective, international, multicentre study. Patients completed a battery of PROMs prior to THA, at three months post-THA, and at one, three, five, and seven-years post-THA. The Harris Hip Score (HHS), the 36-Item Short-Form Health Survey (SF-36) Physical Component Summary (PCS), the SF-36 Mental Component Summary (MCS), and the EuroQol five-dimension three-level (EQ-5D) index were the primary outcomes. Longitudinal changes in each PROM were investigated by piece-wise linear mixed effects models. Clinically significant deterioration was defined for each patient as a decrease of one half of a standard deviation (group baseline). Results Improvements were noted in each PROM between the preoperative and one-year visits, with one-year values exceeding age-matched population norms. Patients with difficulty in self-care experienced less improvement in HHS (odds ratio (OR) 2.2; p = 0.003). Those with anxiety/depression experienced less improvement in PCS (OR -3.3; p = 0.002) and EQ-5D (OR -0.07; p = 0.005). Between one and seven years, obesity was associated with deterioration in HHS (1.5 points/year; p = 0.006), PCS (0.8 points/year; p < 0.001), and EQ-5D (0.02 points/year; p < 0.001). Preoperative difficulty in self-care was associated with deterioration in HHS (2.2 points/year; p < 0.001). Preoperative pain from other joints was associated with deterioration in MCS (0.8 points/year; p < 0.001). All aforementioned factors were associated with clinically significant deterioration in PROMs (p < 0.035), except anxiety/depression with regard to PCS (p = 0.060). Conclusion The present study finds that patient factors affect the improvement and deterioration in PROMs over the medium term following THA. Special attention should be given to patients with risk factors for decreased PROMs, both preoperatively and during follow-up.

KW - Adult

KW - Aged

KW - Arthroplasty, Replacement, Hip

KW - Female

KW - Follow-Up Studies

KW - Humans

KW - Male

KW - Middle Aged

KW - Osteoarthritis, Hip/physiopathology

KW - Patient Reported Outcome Measures

KW - Prospective Studies

KW - Prosthesis Failure/etiology

KW - Treatment Outcome

U2 - 10.1302/0301-620X.101B7.BJJ-2018-1491.R1

DO - 10.1302/0301-620X.101B7.BJJ-2018-1491.R1

M3 - Journal article

C2 - 31256661

SN - 2049-4394

VL - 101-B

SP - 768

EP - 778

JO - Journal of Bone and Joint Surgery: British Volume

JF - Journal of Bone and Joint Surgery: British Volume

IS - 7

ER -

Longitudinal changes in patient-reported outcome measures following total hip arthroplasty and predictors of deterioration during follow-up: a seven-year prospective international multicentre study

Abstract

Keywords

UN SDGs

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