Liver biopsy in liver patients with coagulopathy

P. Ott; H. Gronbaek; M.R. Clausen; Andre' Wettergren; T. Havelund; Erik Feldager Hansen; Flemming Bendtsen; B.A. Hansen; U. Tage-Jensen; L.P. Larsen; H. Vilstrup; Jens Otto Clemmesen

Liver biopsy in liver patients with coagulopathy

P. Ott, H. Gronbaek, M.R. Clausen, Andre' Wettergren, T. Havelund, Erik Feldager Hansen, Flemming Bendtsen, B.A. Hansen, U. Tage-Jensen, L.P. Larsen, H. Vilstrup, Jens Otto Clemmesen

Department of Clinical Medicine

3 Citations (Scopus)

Abstract

The risk of severe bleeding after liver biopsy is estimated to be 1:12,000 in patients with near normal coagulation (INR < 1,5 and platelet count > 60 billion /l). Beyond these limits, the risk is higher, but still uncertain. The Danish guidelines require INR > 1.5, platelet count < 40 billion /l and normal APTT. In some instances the risk of not knowing the histology is so high that a biopsy is considered even with a more disturbed coagulation. Vitamin K, freshly frozen plasma and recombinant activated factor VII may reduce the risk of bleeding in specific situations, but no firm recommendations can be given
Udgivelsesdato: 2008/11/3

Original language	Danish
Journal	Ugeskrift for læger
Volume	170
Issue number	45
Pages (from-to)	3671-3673
Number of pages	2
ISSN	0041-5782
Publication status	Published - 2008

Cite this

@article{24399d608b2511de8bc9000ea68e967b,

title = "Liver biopsy in liver patients with coagulopathy",

abstract = "The risk of severe bleeding after liver biopsy is estimated to be 1:12,000 in patients with near normal coagulation (INR < 1,5 and platelet count > 60 billion /l). Beyond these limits, the risk is higher, but still uncertain. The Danish guidelines require INR > 1.5, platelet count < 40 billion /l and normal APTT. In some instances the risk of not knowing the histology is so high that a biopsy is considered even with a more disturbed coagulation. Vitamin K, freshly frozen plasma and recombinant activated factor VII may reduce the risk of bleeding in specific situations, but no firm recommendations can be given Udgivelsesdato: 2008/11/3",

author = "P. Ott and H. Gronbaek and M.R. Clausen and Andre' Wettergren and T. Havelund and Hansen, {Erik Feldager} and Flemming Bendtsen and B.A. Hansen and U. Tage-Jensen and L.P. Larsen and H. Vilstrup and Clemmesen, {Jens Otto}",

year = "2008",

language = "Dansk",

volume = "170",

pages = "3671--3673",

journal = "Ugeskrift for Laeger",

issn = "0041-5782",

publisher = "Almindelige Danske Laegeforening",

number = "45",

}

TY - JOUR

T1 - Liver biopsy in liver patients with coagulopathy

AU - Ott, P.

AU - Gronbaek, H.

AU - Clausen, M.R.

AU - Wettergren, Andre'

AU - Havelund, T.

AU - Hansen, Erik Feldager

AU - Bendtsen, Flemming

AU - Hansen, B.A.

AU - Tage-Jensen, U.

AU - Larsen, L.P.

AU - Vilstrup, H.

AU - Clemmesen, Jens Otto

PY - 2008

Y1 - 2008

N2 - The risk of severe bleeding after liver biopsy is estimated to be 1:12,000 in patients with near normal coagulation (INR < 1,5 and platelet count > 60 billion /l). Beyond these limits, the risk is higher, but still uncertain. The Danish guidelines require INR > 1.5, platelet count < 40 billion /l and normal APTT. In some instances the risk of not knowing the histology is so high that a biopsy is considered even with a more disturbed coagulation. Vitamin K, freshly frozen plasma and recombinant activated factor VII may reduce the risk of bleeding in specific situations, but no firm recommendations can be given Udgivelsesdato: 2008/11/3

AB - The risk of severe bleeding after liver biopsy is estimated to be 1:12,000 in patients with near normal coagulation (INR < 1,5 and platelet count > 60 billion /l). Beyond these limits, the risk is higher, but still uncertain. The Danish guidelines require INR > 1.5, platelet count < 40 billion /l and normal APTT. In some instances the risk of not knowing the histology is so high that a biopsy is considered even with a more disturbed coagulation. Vitamin K, freshly frozen plasma and recombinant activated factor VII may reduce the risk of bleeding in specific situations, but no firm recommendations can be given Udgivelsesdato: 2008/11/3

M3 - Tidsskriftartikel

SN - 0041-5782

VL - 170

SP - 3671

EP - 3673

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

IS - 45

ER -