Leg length, sitting height and postmenopausal breast cancer risk

L Mellemkjær; J Christensen; K Frederiksen; J L Baker; A Olsen; T I A Sørensen; A Tjønneland

doi:10.1038/bjc.2012.244

Leg length, sitting height and postmenopausal breast cancer risk

L Mellemkjær, J Christensen, K Frederiksen, J L Baker, A Olsen, T I A Sørensen, A Tjønneland

9 Citations (Scopus)

Abstract

Background: Tallness has consistently been associated with an increased risk of breast cancer. We investigated the association further by decomposing height into leg length and sitting height. Methods: From the prospective Danish cohort Diet, Cancer and Health, 23 864 postmenopausal women enrolled during 1993-1997 were followed for a diagnosis of breast cancer in the Danish Cancer Registry through 2009. Results: The incidence rate ratios for breast cancer were 1.11 (95% CI=1.06-1.16) for each 5 cm increase in total height and 1.09 (95% CI=1.01-1.17) and 1.14 (95% CI=1.04-1.25) for each 5 cm increase in leg length and sitting height, respectively. There was no statistical significant difference between the associations for leg length and sitting height (P=0.47). Conclusion: Leg length does not seem to be more strongly associated with breast cancer among postmenopausal women than sitting height.

Original language	English
Journal	B J C
Volume	107
Issue number	1
Pages (from-to)	165-8
Number of pages	4
ISSN	0007-0920
DOIs	https://doi.org/10.1038/bjc.2012.244
Publication status	Published - 26 Jun 2012

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title = "Leg length, sitting height and postmenopausal breast cancer risk",

abstract = "Background: Tallness has consistently been associated with an increased risk of breast cancer. We investigated the association further by decomposing height into leg length and sitting height. Methods: From the prospective Danish cohort Diet, Cancer and Health, 23 864 postmenopausal women enrolled during 1993-1997 were followed for a diagnosis of breast cancer in the Danish Cancer Registry through 2009. Results: The incidence rate ratios for breast cancer were 1.11 (95% CI=1.06-1.16) for each 5 cm increase in total height and 1.09 (95% CI=1.01-1.17) and 1.14 (95% CI=1.04-1.25) for each 5 cm increase in leg length and sitting height, respectively. There was no statistical significant difference between the associations for leg length and sitting height (P=0.47). Conclusion: Leg length does not seem to be more strongly associated with breast cancer among postmenopausal women than sitting height.",

author = "L Mellemkj{\ae}r and J Christensen and K Frederiksen and Baker, {J L} and A Olsen and S{\o}rensen, {T I A} and A Tj{\o}nneland",

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doi = "10.1038/bjc.2012.244",

language = "English",

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TY - JOUR

T1 - Leg length, sitting height and postmenopausal breast cancer risk

AU - Mellemkjær, L

AU - Christensen, J

AU - Frederiksen, K

AU - Baker, J L

AU - Olsen, A

AU - Sørensen, T I A

AU - Tjønneland, A

PY - 2012/6/26

Y1 - 2012/6/26

N2 - Background: Tallness has consistently been associated with an increased risk of breast cancer. We investigated the association further by decomposing height into leg length and sitting height. Methods: From the prospective Danish cohort Diet, Cancer and Health, 23 864 postmenopausal women enrolled during 1993-1997 were followed for a diagnosis of breast cancer in the Danish Cancer Registry through 2009. Results: The incidence rate ratios for breast cancer were 1.11 (95% CI=1.06-1.16) for each 5 cm increase in total height and 1.09 (95% CI=1.01-1.17) and 1.14 (95% CI=1.04-1.25) for each 5 cm increase in leg length and sitting height, respectively. There was no statistical significant difference between the associations for leg length and sitting height (P=0.47). Conclusion: Leg length does not seem to be more strongly associated with breast cancer among postmenopausal women than sitting height.

AB - Background: Tallness has consistently been associated with an increased risk of breast cancer. We investigated the association further by decomposing height into leg length and sitting height. Methods: From the prospective Danish cohort Diet, Cancer and Health, 23 864 postmenopausal women enrolled during 1993-1997 were followed for a diagnosis of breast cancer in the Danish Cancer Registry through 2009. Results: The incidence rate ratios for breast cancer were 1.11 (95% CI=1.06-1.16) for each 5 cm increase in total height and 1.09 (95% CI=1.01-1.17) and 1.14 (95% CI=1.04-1.25) for each 5 cm increase in leg length and sitting height, respectively. There was no statistical significant difference between the associations for leg length and sitting height (P=0.47). Conclusion: Leg length does not seem to be more strongly associated with breast cancer among postmenopausal women than sitting height.

U2 - 10.1038/bjc.2012.244

DO - 10.1038/bjc.2012.244

M3 - Journal article

SN - 0007-0920

VL - 107

SP - 165

EP - 168

JO - The British journal of cancer. Supplement

JF - The British journal of cancer. Supplement

IS - 1

ER -

Leg length, sitting height and postmenopausal breast cancer risk

Abstract

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