TY - JOUR
T1 - Laboratory exposure to Brucella melitensis in Denmark
T2 - a prospective study
AU - Knudsen, A
AU - Kronborg, G
AU - Knudsen, Inge Jenny Dahl
AU - Lebech, A-M
PY - 2013/11
Y1 - 2013/11
N2 - Brucella species are a frequent cause of laboratory-acquired infections. This report describes the handling of a laboratory exposure of 17 laboratory staff members exposed to Brucella melitensis in a large microbiology laboratory in a brucella-non-endemic area. We followed the US Centers for Disease Control and Prevention guidelines, but, of 14 staff members classified as high-risk exposure, none accepted post-exposure prophylaxis. However, in a period of 6 months of follow-up, none of the exposed laboratory workers developed brucellosis and all obtained sera were negative for antibrucella antibodies. We therefore question the value of routine serological follow-up.
AB - Brucella species are a frequent cause of laboratory-acquired infections. This report describes the handling of a laboratory exposure of 17 laboratory staff members exposed to Brucella melitensis in a large microbiology laboratory in a brucella-non-endemic area. We followed the US Centers for Disease Control and Prevention guidelines, but, of 14 staff members classified as high-risk exposure, none accepted post-exposure prophylaxis. However, in a period of 6 months of follow-up, none of the exposed laboratory workers developed brucellosis and all obtained sera were negative for antibrucella antibodies. We therefore question the value of routine serological follow-up.
U2 - 10.1016/j.jhin.2013.08.005
DO - 10.1016/j.jhin.2013.08.005
M3 - Journal article
C2 - 24070633
SN - 0195-6701
VL - 85
SP - 237
EP - 239
JO - Journal of Hospital Infection
JF - Journal of Hospital Infection
IS - 3
ER -