Joint sequencing of human and pathogen genomes reveals the genetics of pneumococcal meningitis

John A. Lees; Bart Ferwerda; Philip H. C. Kremer; Nicole E. Wheeler; Mercedes Valls Seron; Nicholas J. Croucher; Rebecca A. Gladstone; Hester J. Bootsma; Nynke Y. Rots; Alienke J. Wijmega-Monsuur; Elisabeth A. M. Sanders; Krzysztof Trzcinski; Anne L. Wyllie; Aeilko H. Zwinderman; Leonard H. van den Berg; Wouter van Rheenen; Jan H. Veldink; Zitta B. Harboe; Lene F. Lundbo; Lisette C. P. G. M. de Groot; Natasja M. van Schoor; Nathalie van der Velde; Lars H. Angquist; Thorkild I. A. Sørensen; Ellen A. Nohr; Alexander J. Mentzer; Tara C. Mills; Julian C. Knight; Mignon du Plessis; Susan Nzenze; Jeffrey N. Weiser; Julian Parkhill; Shabir Madhi; Thomas Benfield; Anne von Gottberg; Arie van der Ende; Matthijs C. Brouwer; Jeffrey C. Barrett; Stephen D. Bentley; Diederik van de Beek

doi:10.1038/s41467-019-09976-3

Joint sequencing of human and pathogen genomes reveals the genetics of pneumococcal meningitis

John A. Lees, Bart Ferwerda, Philip H. C. Kremer, Nicole E. Wheeler, Mercedes Valls Seron, Nicholas J. Croucher, Rebecca A. Gladstone, Hester J. Bootsma, Nynke Y. Rots, Alienke J. Wijmega-Monsuur, Elisabeth A. M. Sanders, Krzysztof Trzcinski, Anne L. Wyllie, Aeilko H. Zwinderman, Leonard H. van den Berg, Wouter van Rheenen, Jan H. Veldink, Zitta B. Harboe, Lene F. Lundbo, Lisette C. P. G. M. de GrootNatasja M. van Schoor, Nathalie van der Velde, Lars H. Angquist, Thorkild I. A. Sørensen, Ellen A. Nohr, Alexander J. Mentzer, Tara C. Mills, Julian C. Knight, Mignon du Plessis, Susan Nzenze, Jeffrey N. Weiser, Julian Parkhill, Shabir Madhi, Thomas Benfield, Anne von Gottberg, Arie van der Ende, Matthijs C. Brouwer, Jeffrey C. Barrett, Stephen D. Bentley, Diederik van de Beek

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Original language	English
Article number	2176
Journal	Nature Communications
Volume	10
Number of pages	14
ISSN	2041-1723
DOIs	https://doi.org/10.1038/s41467-019-09976-3
Publication status	Published - 1 Dec 2019

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Joint sequencing of human and pathogen genomes reveals the genetics of pneumococcal meningitisFinal published version, 4.87 MBLicence: CC BY

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Lees, J. A., Ferwerda, B., Kremer, P. H. C., Wheeler, N. E., Seron, M. V., Croucher, N. J., Gladstone, R. A., Bootsma, H. J., Rots, N. Y., Wijmega-Monsuur, A. J., Sanders, E. A. M., Trzcinski, K., Wyllie, A. L., Zwinderman, A. H., van den Berg, L. H., van Rheenen, W., Veldink, J. H., Harboe, Z. B., Lundbo, L. F., ... van de Beek, D. (2019). Joint sequencing of human and pathogen genomes reveals the genetics of pneumococcal meningitis. Nature Communications, 10, Article 2176. https://doi.org/10.1038/s41467-019-09976-3

Lees, JA, Ferwerda, B, Kremer, PHC, Wheeler, NE, Seron, MV, Croucher, NJ, Gladstone, RA, Bootsma, HJ, Rots, NY, Wijmega-Monsuur, AJ, Sanders, EAM, Trzcinski, K, Wyllie, AL, Zwinderman, AH, van den Berg, LH, van Rheenen, W, Veldink, JH, Harboe, ZB, Lundbo, LF, de Groot, LCPGM, van Schoor, NM, van der Velde, N, Angquist, LH , Sørensen, TIA, Nohr, EA, Mentzer, AJ, Mills, TC, Knight, JC, du Plessis, M, Nzenze, S, Weiser, JN, Parkhill, J, Madhi, S, Benfield, T, von Gottberg, A, van der Ende, A, Brouwer, MC, Barrett, JC, Bentley, SD & van de Beek, D 2019, 'Joint sequencing of human and pathogen genomes reveals the genetics of pneumococcal meningitis', Nature Communications, vol. 10, 2176. https://doi.org/10.1038/s41467-019-09976-3

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title = "Joint sequencing of human and pathogen genomes reveals the genetics of pneumococcal meningitis",

author = "Lees, {John A.} and Bart Ferwerda and Kremer, {Philip H. C.} and Wheeler, {Nicole E.} and Seron, {Mercedes Valls} and Croucher, {Nicholas J.} and Gladstone, {Rebecca A.} and Bootsma, {Hester J.} and Rots, {Nynke Y.} and Wijmega-Monsuur, {Alienke J.} and Sanders, {Elisabeth A. M.} and Krzysztof Trzcinski and Wyllie, {Anne L.} and Zwinderman, {Aeilko H.} and {van den Berg}, {Leonard H.} and {van Rheenen}, Wouter and Veldink, {Jan H.} and Harboe, {Zitta B.} and Lundbo, {Lene F.} and {de Groot}, {Lisette C. P. G. M.} and {van Schoor}, {Natasja M.} and {van der Velde}, Nathalie and Angquist, {Lars H.} and S{\o}rensen, {Thorkild I. A.} and Nohr, {Ellen A.} and Mentzer, {Alexander J.} and Mills, {Tara C.} and Knight, {Julian C.} and {du Plessis}, Mignon and Susan Nzenze and Weiser, {Jeffrey N.} and Julian Parkhill and Shabir Madhi and Thomas Benfield and {von Gottberg}, Anne and {van der Ende}, Arie and Brouwer, {Matthijs C.} and Barrett, {Jeffrey C.} and Bentley, {Stephen D.} and {van de Beek}, Diederik",

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T1 - Joint sequencing of human and pathogen genomes reveals the genetics of pneumococcal meningitis

AU - Lees, John A.

AU - Ferwerda, Bart

AU - Kremer, Philip H. C.

AU - Wheeler, Nicole E.

AU - Seron, Mercedes Valls

AU - Croucher, Nicholas J.

AU - Gladstone, Rebecca A.

AU - Bootsma, Hester J.

AU - Rots, Nynke Y.

AU - Wijmega-Monsuur, Alienke J.

AU - Sanders, Elisabeth A. M.

AU - Trzcinski, Krzysztof

AU - Wyllie, Anne L.

AU - Zwinderman, Aeilko H.

AU - van den Berg, Leonard H.

AU - van Rheenen, Wouter

AU - Veldink, Jan H.

AU - Harboe, Zitta B.

AU - Lundbo, Lene F.

AU - de Groot, Lisette C. P. G. M.

AU - van Schoor, Natasja M.

AU - van der Velde, Nathalie

AU - Angquist, Lars H.

AU - Sørensen, Thorkild I. A.

AU - Nohr, Ellen A.

AU - Mentzer, Alexander J.

AU - Mills, Tara C.

AU - Knight, Julian C.

AU - du Plessis, Mignon

AU - Nzenze, Susan

AU - Weiser, Jeffrey N.

AU - Parkhill, Julian

AU - Madhi, Shabir

AU - Benfield, Thomas

AU - von Gottberg, Anne

AU - van der Ende, Arie

AU - Brouwer, Matthijs C.

AU - Barrett, Jeffrey C.

AU - Bentley, Stephen D.

AU - van de Beek, Diederik

PY - 2019/12/1

Y1 - 2019/12/1

U2 - 10.1038/s41467-019-09976-3

DO - 10.1038/s41467-019-09976-3

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C2 - 31092817

SN - 2041-1723

VL - 10

JO - Nature Communications

JF - Nature Communications

M1 - 2176

ER -

Joint sequencing of human and pathogen genomes reveals the genetics of pneumococcal meningitis

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