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Investigating the molecular mechanism of positive and negative allosteric modulators in the calcium-sensing receptor dimer
Stine Engesgaard Jacobsen,
Ulrik Gether
,
Hans Bräuner-Osborne
Neuropharm and Genetics
15
Citations (Scopus)
79
Downloads (Pure)
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Dive into the research topics of 'Investigating the molecular mechanism of positive and negative allosteric modulators in the calcium-sensing receptor dimer'. Together they form a unique fingerprint.
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Keyphrases
Positive Allosteric Modulator
100%
Receptor Dimerization
100%
Negative Allosteric Modulator
100%
Molecular Mechanism
100%
Calcium-sensing Receptor (CaSR)
100%
Allosteric Site
75%
Transactivation
50%
Activation Mechanism
50%
Metabotropic Glutamate Receptor
50%
Therapeutic Potential
25%
Novel Therapeutics
25%
Allosteric Modulation
25%
G Protein Coupling
25%
Allosteric Modulator
25%
Receptor Activity
25%
Gain-of-function mutation
25%
Transmembrane Domain
25%
Well-defined
25%
Biochemistry, Genetics and Molecular Biology
Calcium-Sensing Receptor
100%
Allosteric Site
75%
Glutamate Receptor
50%
Transactivation
50%
Transmembrane Domain
25%
Agonist
25%
G Protein Coupled Receptor
25%
G Protein
25%