International Veterinary Epilepsy Task Force consensus proposal: medical treatment of canine epilepsy in Europe

Sofie F M Bhatti; Luisa De Risio; Karen Muñana; Jacques Penderis; Veronika M Stein; Andrea Tipold; Mette Berendt; Robyn G Farquhar; Andrea Fischer; Sam Long; Wolfgang Löscher; Paul J J Mandigers; Kaspar Matiasek; Akos Pakozdy; Edward E Patterson; Simon Platt; Michael Podell; Heidrun Potschka; Clare Rusbridge; Holger A Volk

doi:10.1186/s12917-015-0464-z

International Veterinary Epilepsy Task Force consensus proposal: medical treatment of canine epilepsy in Europe

Sofie F M Bhatti, Luisa De Risio, Karen Muñana, Jacques Penderis, Veronika M Stein, Andrea Tipold, Mette Berendt, Robyn G Farquhar, Andrea Fischer, Sam Long, Wolfgang Löscher, Paul J J Mandigers, Kaspar Matiasek, Akos Pakozdy, Edward E Patterson, Simon Platt, Michael Podell, Heidrun Potschka, Clare Rusbridge, Holger A Volk

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Abstract

In Europe, the number of antiepileptic drugs (AEDs) licensed for dogs has grown considerably over the last years. Nevertheless, the same questions remain, which include, 1) when to start treatment, 2) which drug is best used initially, 3) which adjunctive AED can be advised if treatment with the initial drug is unsatisfactory, and 4) when treatment changes should be considered. In this consensus proposal, an overview is given on the aim of AED treatment, when to start long-term treatment in canine epilepsy and which veterinary AEDs are currently in use for dogs. The consensus proposal for drug treatment protocols, 1) is based on current published evidence-based literature, 2) considers the current legal framework of the cascade regulation for the prescription of veterinary drugs in Europe, and 3) reflects the authors' experience. With this paper it is aimed to provide a consensus for the management of canine idiopathic epilepsy. Furthermore, for the management of structural epilepsy AEDs are inevitable in addition to treating the underlying cause, if possible.

Original language	English
Article number	176
Journal	B M C Veterinary Research
Volume	11
Number of pages	16
ISSN	1746-6148
DOIs	https://doi.org/10.1186/s12917-015-0464-z
Publication status	Published - 28 Aug 2015

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Bhatti, S. F. M., De Risio, L., Muñana, K., Penderis, J., Stein, V. M., Tipold, A., Berendt, M., Farquhar, R. G., Fischer, A., Long, S., Löscher, W., Mandigers, P. J. J., Matiasek, K., Pakozdy, A., Patterson, E. E., Platt, S., Podell, M., Potschka, H., Rusbridge, C., & Volk, H. A. (2015). International Veterinary Epilepsy Task Force consensus proposal: medical treatment of canine epilepsy in Europe. B M C Veterinary Research, 11, [176]. https://doi.org/10.1186/s12917-015-0464-z

Bhatti, SFM, De Risio, L, Muñana, K, Penderis, J, Stein, VM, Tipold, A, Berendt, M, Farquhar, RG, Fischer, A, Long, S, Löscher, W, Mandigers, PJJ, Matiasek, K, Pakozdy, A, Patterson, EE, Platt, S, Podell, M, Potschka, H, Rusbridge, C & Volk, HA 2015, 'International Veterinary Epilepsy Task Force consensus proposal: medical treatment of canine epilepsy in Europe', B M C Veterinary Research, vol. 11, 176. https://doi.org/10.1186/s12917-015-0464-z

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title = "International Veterinary Epilepsy Task Force consensus proposal: medical treatment of canine epilepsy in Europe",

abstract = "In Europe, the number of antiepileptic drugs (AEDs) licensed for dogs has grown considerably over the last years. Nevertheless, the same questions remain, which include, 1) when to start treatment, 2) which drug is best used initially, 3) which adjunctive AED can be advised if treatment with the initial drug is unsatisfactory, and 4) when treatment changes should be considered. In this consensus proposal, an overview is given on the aim of AED treatment, when to start long-term treatment in canine epilepsy and which veterinary AEDs are currently in use for dogs. The consensus proposal for drug treatment protocols, 1) is based on current published evidence-based literature, 2) considers the current legal framework of the cascade regulation for the prescription of veterinary drugs in Europe, and 3) reflects the authors' experience. With this paper it is aimed to provide a consensus for the management of canine idiopathic epilepsy. Furthermore, for the management of structural epilepsy AEDs are inevitable in addition to treating the underlying cause, if possible.",

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AU - Penderis, Jacques

AU - Stein, Veronika M

AU - Tipold, Andrea

AU - Berendt, Mette

AU - Farquhar, Robyn G

AU - Fischer, Andrea

AU - Long, Sam

AU - Löscher, Wolfgang

AU - Mandigers, Paul J J

AU - Matiasek, Kaspar

AU - Pakozdy, Akos

AU - Patterson, Edward E

AU - Platt, Simon

AU - Podell, Michael

AU - Potschka, Heidrun

AU - Rusbridge, Clare

AU - Volk, Holger A

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N2 - In Europe, the number of antiepileptic drugs (AEDs) licensed for dogs has grown considerably over the last years. Nevertheless, the same questions remain, which include, 1) when to start treatment, 2) which drug is best used initially, 3) which adjunctive AED can be advised if treatment with the initial drug is unsatisfactory, and 4) when treatment changes should be considered. In this consensus proposal, an overview is given on the aim of AED treatment, when to start long-term treatment in canine epilepsy and which veterinary AEDs are currently in use for dogs. The consensus proposal for drug treatment protocols, 1) is based on current published evidence-based literature, 2) considers the current legal framework of the cascade regulation for the prescription of veterinary drugs in Europe, and 3) reflects the authors' experience. With this paper it is aimed to provide a consensus for the management of canine idiopathic epilepsy. Furthermore, for the management of structural epilepsy AEDs are inevitable in addition to treating the underlying cause, if possible.

AB - In Europe, the number of antiepileptic drugs (AEDs) licensed for dogs has grown considerably over the last years. Nevertheless, the same questions remain, which include, 1) when to start treatment, 2) which drug is best used initially, 3) which adjunctive AED can be advised if treatment with the initial drug is unsatisfactory, and 4) when treatment changes should be considered. In this consensus proposal, an overview is given on the aim of AED treatment, when to start long-term treatment in canine epilepsy and which veterinary AEDs are currently in use for dogs. The consensus proposal for drug treatment protocols, 1) is based on current published evidence-based literature, 2) considers the current legal framework of the cascade regulation for the prescription of veterinary drugs in Europe, and 3) reflects the authors' experience. With this paper it is aimed to provide a consensus for the management of canine idiopathic epilepsy. Furthermore, for the management of structural epilepsy AEDs are inevitable in addition to treating the underlying cause, if possible.

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DO - 10.1186/s12917-015-0464-z

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SN - 1746-6148

VL - 11

JO - B M C Veterinary Research

JF - B M C Veterinary Research

M1 - 176

ER -

International Veterinary Epilepsy Task Force consensus proposal: medical treatment of canine epilepsy in Europe

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