International variations in the gestational age distribution of births: an ecological study in 34 high-income countries

Marie Delnord; Laust Mortensen; Ashna D. Hindori-mohangoo; Béatrice Blondel; Mika Gissler; Michael R. Kramer; Jennifer L. Richards; Paromita Deb-Rinker; Jocelyn Rouleau; Naho Morisaki; Natasha Nassar; Francisco Bolumar; Sylvie Berrut; Anne-Marie Nybo Andersen; Michael S. Kramer; Jennifer Zeitlin; Euro-Peristat Scientific Committee

doi:10.1093/eurpub/ckx131

International variations in the gestational age distribution of births: an ecological study in 34 high-income countries

Marie Delnord, Laust Mortensen, Ashna D. Hindori-mohangoo, Béatrice Blondel, Mika Gissler, Michael R. Kramer, Jennifer L. Richards, Paromita Deb-Rinker, Jocelyn Rouleau, Naho Morisaki, Natasha Nassar, Francisco Bolumar, Sylvie Berrut, Anne-Marie Nybo Andersen, Michael S. Kramer, Jennifer Zeitlin, Euro-Peristat Scientific Committee

10 Citations (Scopus)

Abstract

Background: Few studies have investigated international variations in the gestational age (GA) distribution of births. While preterm births (22-36 weeks GA) and early term births (37-38 weeks) are at greater risk of adverse health outcomes compared to full term births (39-40 weeks), it is not known if countries with high preterm birth rates also have high early term birth rates. We examined rate associations between preterm and early term births and mean term GA by mode of delivery onset. Methods: We used routine aggregate data on the GA distribution of singleton live births from up to 34 high-income countries/regions in 1996, 2000, 2004, 2008 and 2010 to study preterm and early term births overall and by spontaneous or indicated onset. Pearson correlation coefficients were adjusted for clustering in time trend analyses. Results: Preterm and early term births ranged from 4.1% to 8.2% (median 5.5%) and 15.6% to 30.8% (median 22.2%) of live births in 2010, respectively. Countries with higher preterm birth rates in 2004-2010 had higher early term birth rates (r > 0.50, P < 0.01) and changes over time were strongly correlated overall (adjusted-r=0.55, P < 0.01) and by mode of onset. Conclusion: Positive associations between preterm and early term birth rates suggest that common risk factors could underpin shifts in the GA distribution. Targeting modifiable population risk factors for delivery before 39 weeks GA may provide a useful preterm birth prevention paradigm.

Original language	English
Journal	European Journal of Public Health
Volume	28
Issue number	2
Pages (from-to)	303-309
Number of pages	7
ISSN	1101-1262
DOIs	https://doi.org/10.1093/eurpub/ckx131
Publication status	Published - 1 Apr 2018

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Delnord, M., Mortensen, L., Hindori-mohangoo, A. D., Blondel, B., Gissler, M., Kramer, M. R., Richards, J. L., Deb-Rinker, P., Rouleau, J., Morisaki, N., Nassar, N., Bolumar, F., Berrut, S., Nybo Andersen, A.-M., Kramer, M. S., Zeitlin, J., & Euro-Peristat Scientific Committee (2018). International variations in the gestational age distribution of births: an ecological study in 34 high-income countries. European Journal of Public Health, 28(2), 303-309. https://doi.org/10.1093/eurpub/ckx131

Delnord, M, Mortensen, L, Hindori-mohangoo, AD, Blondel, B, Gissler, M, Kramer, MR, Richards, JL, Deb-Rinker, P, Rouleau, J, Morisaki, N, Nassar, N, Bolumar, F, Berrut, S, Nybo Andersen, A-M, Kramer, MS, Zeitlin, J & Euro-Peristat Scientific Committee 2018, 'International variations in the gestational age distribution of births: an ecological study in 34 high-income countries', European Journal of Public Health, vol. 28, no. 2, pp. 303-309. https://doi.org/10.1093/eurpub/ckx131

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title = "International variations in the gestational age distribution of births: an ecological study in 34 high-income countries",

abstract = "Background: Few studies have investigated international variations in the gestational age (GA) distribution of births. While preterm births (22-36 weeks GA) and early term births (37-38 weeks) are at greater risk of adverse health outcomes compared to full term births (39-40 weeks), it is not known if countries with high preterm birth rates also have high early term birth rates. We examined rate associations between preterm and early term births and mean term GA by mode of delivery onset. Methods: We used routine aggregate data on the GA distribution of singleton live births from up to 34 high-income countries/regions in 1996, 2000, 2004, 2008 and 2010 to study preterm and early term births overall and by spontaneous or indicated onset. Pearson correlation coefficients were adjusted for clustering in time trend analyses. Results: Preterm and early term births ranged from 4.1% to 8.2% (median 5.5%) and 15.6% to 30.8% (median 22.2%) of live births in 2010, respectively. Countries with higher preterm birth rates in 2004-2010 had higher early term birth rates (r > 0.50, P < 0.01) and changes over time were strongly correlated overall (adjusted-r=0.55, P < 0.01) and by mode of onset. Conclusion: Positive associations between preterm and early term birth rates suggest that common risk factors could underpin shifts in the GA distribution. Targeting modifiable population risk factors for delivery before 39 weeks GA may provide a useful preterm birth prevention paradigm.",

author = "Marie Delnord and Laust Mortensen and Hindori-mohangoo, {Ashna D.} and B{\'e}atrice Blondel and Mika Gissler and Kramer, {Michael R.} and Richards, {Jennifer L.} and Paromita Deb-Rinker and Jocelyn Rouleau and Naho Morisaki and Natasha Nassar and Francisco Bolumar and Sylvie Berrut and {Nybo Andersen}, Anne-Marie and Kramer, {Michael S.} and Jennifer Zeitlin and {Euro-Peristat Scientific Committee}",

year = "2018",

month = apr,

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doi = "10.1093/eurpub/ckx131",

language = "English",

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T1 - International variations in the gestational age distribution of births

T2 - an ecological study in 34 high-income countries

AU - Delnord, Marie

AU - Mortensen, Laust

AU - Hindori-mohangoo, Ashna D.

AU - Blondel, Béatrice

AU - Gissler, Mika

AU - Kramer, Michael R.

AU - Richards, Jennifer L.

AU - Deb-Rinker, Paromita

AU - Rouleau, Jocelyn

AU - Morisaki, Naho

AU - Nassar, Natasha

AU - Bolumar, Francisco

AU - Berrut, Sylvie

AU - Nybo Andersen, Anne-Marie

AU - Kramer, Michael S.

AU - Zeitlin, Jennifer

AU - Euro-Peristat Scientific Committee

PY - 2018/4/1

Y1 - 2018/4/1

N2 - Background: Few studies have investigated international variations in the gestational age (GA) distribution of births. While preterm births (22-36 weeks GA) and early term births (37-38 weeks) are at greater risk of adverse health outcomes compared to full term births (39-40 weeks), it is not known if countries with high preterm birth rates also have high early term birth rates. We examined rate associations between preterm and early term births and mean term GA by mode of delivery onset. Methods: We used routine aggregate data on the GA distribution of singleton live births from up to 34 high-income countries/regions in 1996, 2000, 2004, 2008 and 2010 to study preterm and early term births overall and by spontaneous or indicated onset. Pearson correlation coefficients were adjusted for clustering in time trend analyses. Results: Preterm and early term births ranged from 4.1% to 8.2% (median 5.5%) and 15.6% to 30.8% (median 22.2%) of live births in 2010, respectively. Countries with higher preterm birth rates in 2004-2010 had higher early term birth rates (r > 0.50, P < 0.01) and changes over time were strongly correlated overall (adjusted-r=0.55, P < 0.01) and by mode of onset. Conclusion: Positive associations between preterm and early term birth rates suggest that common risk factors could underpin shifts in the GA distribution. Targeting modifiable population risk factors for delivery before 39 weeks GA may provide a useful preterm birth prevention paradigm.

AB - Background: Few studies have investigated international variations in the gestational age (GA) distribution of births. While preterm births (22-36 weeks GA) and early term births (37-38 weeks) are at greater risk of adverse health outcomes compared to full term births (39-40 weeks), it is not known if countries with high preterm birth rates also have high early term birth rates. We examined rate associations between preterm and early term births and mean term GA by mode of delivery onset. Methods: We used routine aggregate data on the GA distribution of singleton live births from up to 34 high-income countries/regions in 1996, 2000, 2004, 2008 and 2010 to study preterm and early term births overall and by spontaneous or indicated onset. Pearson correlation coefficients were adjusted for clustering in time trend analyses. Results: Preterm and early term births ranged from 4.1% to 8.2% (median 5.5%) and 15.6% to 30.8% (median 22.2%) of live births in 2010, respectively. Countries with higher preterm birth rates in 2004-2010 had higher early term birth rates (r > 0.50, P < 0.01) and changes over time were strongly correlated overall (adjusted-r=0.55, P < 0.01) and by mode of onset. Conclusion: Positive associations between preterm and early term birth rates suggest that common risk factors could underpin shifts in the GA distribution. Targeting modifiable population risk factors for delivery before 39 weeks GA may provide a useful preterm birth prevention paradigm.

U2 - 10.1093/eurpub/ckx131

DO - 10.1093/eurpub/ckx131

M3 - Journal article

C2 - 29020399

SN - 1101-1262

VL - 28

SP - 303

EP - 309

JO - European Journal of Public Health

JF - European Journal of Public Health

IS - 2

ER -

International variations in the gestational age distribution of births: an ecological study in 34 high-income countries

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