Interleukin-37 treatment of mice with metabolic syndrome improves insulin sensitivity and reduces pro-inflammatory cytokine production in adipose tissue

Dov B. Ballak; Suzhao Li; Giulio Cavalli; Jonathan L. Stahl; Isak W. Tengesdal; Janna A. van Diepen; Viola Kluck; Benjamin Swartzwelter; Tania Azam; Cees J. Tack; Rinke Stienstra; Thomas Mandrup-Poulsen; Douglas R. Seals; Charles A. Dinarello

doi:10.1074/jbc.ra118.003698

Interleukin-37 treatment of mice with metabolic syndrome improves insulin sensitivity and reduces pro-inflammatory cytokine production in adipose tissue

Dov B. Ballak, Suzhao Li, Giulio Cavalli, Jonathan L. Stahl, Isak W. Tengesdal, Janna A. van Diepen, Viola Kluck, Benjamin Swartzwelter, Tania Azam, Cees J. Tack, Rinke Stienstra, Thomas Mandrup-Poulsen, Douglas R. Seals, Charles A. Dinarello

19 Citations (Scopus)

Original language	English
Journal	Journal of Biological Chemistry
Volume	293
Issue number	37
Pages (from-to)	14224-14236
ISSN	0021-9258
DOIs	https://doi.org/10.1074/jbc.ra118.003698
Publication status	Published - 14 Sept 2018

Keywords

adipose tissue
inflammation
cytokine
drug development
insulin resistance
glucose metabolism
mouse
type 2 diabetes
cellular research
mouse model

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1074/jbc.ra118.003698

http://www.jbc.org/content/293/37/14224.full.pdfLicence: CC BY

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Ballak, D. B., Li, S., Cavalli, G., Stahl, J. L., Tengesdal, I. W., van Diepen, J. A., Kluck, V., Swartzwelter, B., Azam, T., Tack, C. J., Stienstra, R., Mandrup-Poulsen, T., Seals, D. R., & Dinarello, C. A. (2018). Interleukin-37 treatment of mice with metabolic syndrome improves insulin sensitivity and reduces pro-inflammatory cytokine production in adipose tissue. Journal of Biological Chemistry, 293(37), 14224-14236. https://doi.org/10.1074/jbc.ra118.003698

Interleukin-37 treatment of mice with metabolic syndrome improves insulin sensitivity and reduces pro-inflammatory cytokine production in adipose tissue. / Ballak, Dov B.; Li, Suzhao; Cavalli, Giulio et al.

In: Journal of Biological Chemistry, Vol. 293, No. 37, 14.09.2018, p. 14224-14236.

Research output: Contribution to journal › Journal article › Research › peer-review

Ballak, DB, Li, S, Cavalli, G, Stahl, JL, Tengesdal, IW, van Diepen, JA, Kluck, V, Swartzwelter, B, Azam, T, Tack, CJ, Stienstra, R, Mandrup-Poulsen, T, Seals, DR & Dinarello, CA 2018, 'Interleukin-37 treatment of mice with metabolic syndrome improves insulin sensitivity and reduces pro-inflammatory cytokine production in adipose tissue', Journal of Biological Chemistry, vol. 293, no. 37, pp. 14224-14236. https://doi.org/10.1074/jbc.ra118.003698

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title = "Interleukin-37 treatment of mice with metabolic syndrome improves insulin sensitivity and reduces pro-inflammatory cytokine production in adipose tissue",

keywords = "adipose tissue, inflammation, cytokine, drug development, insulin resistance, glucose metabolism, mouse, type 2 diabetes, cellular research, mouse model",

author = "Ballak, {Dov B.} and Suzhao Li and Giulio Cavalli and Stahl, {Jonathan L.} and Tengesdal, {Isak W.} and {van Diepen}, {Janna A.} and Viola Kluck and Benjamin Swartzwelter and Tania Azam and Tack, {Cees J.} and Rinke Stienstra and Thomas Mandrup-Poulsen and Seals, {Douglas R.} and Dinarello, {Charles A.}",

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T1 - Interleukin-37 treatment of mice with metabolic syndrome improves insulin sensitivity and reduces pro-inflammatory cytokine production in adipose tissue

AU - Ballak, Dov B.

AU - Li, Suzhao

AU - Cavalli, Giulio

AU - Stahl, Jonathan L.

AU - Tengesdal, Isak W.

AU - van Diepen, Janna A.

AU - Kluck, Viola

AU - Swartzwelter, Benjamin

AU - Azam, Tania

AU - Tack, Cees J.

AU - Stienstra, Rinke

AU - Mandrup-Poulsen, Thomas

AU - Seals, Douglas R.

AU - Dinarello, Charles A.

PY - 2018/9/14

Y1 - 2018/9/14

KW - adipose tissue

KW - inflammation

KW - cytokine

KW - drug development

KW - insulin resistance

KW - glucose metabolism

KW - mouse

KW - type 2 diabetes

KW - cellular research

KW - mouse model

U2 - 10.1074/jbc.ra118.003698

DO - 10.1074/jbc.ra118.003698

M3 - Journal article

C2 - 30006351

SN - 0021-9258

VL - 293

SP - 14224

EP - 14236

JO - Journal of Biological Chemistry

JF - Journal of Biological Chemistry

IS - 37

ER -

Interleukin-37 treatment of mice with metabolic syndrome improves insulin sensitivity and reduces pro-inflammatory cytokine production in adipose tissue

Keywords

UN SDGs

Access to Document

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