Interference microscopy under double-wavelet analysis: a new approach to studying cell dynamics

Olga Sosnovtseva; A N Pavlov; Nadezda Brazhe; Alexey Brazhe; L A Erokhova; G V Maksimov; Erik Mosekilde

Interference microscopy under double-wavelet analysis: a new approach to studying cell dynamics

Olga Sosnovtseva, A N Pavlov, Nadezda Brazhe, Alexey Brazhe, L A Erokhova, G V Maksimov, Erik Mosekilde

Renal and Vascular Research

31 Citations (Scopus)

Abstract

This Letter combines a novel experimental approach to the study of intracellular processes with a newly developed technique for multimode time-series analysis. Experiments are performed on isolated pond snail (Lymnaea stagnalis) neurons. Local variations in the cellular refractive index as detected by laser interference microscopy are related to the processes in the cell. A wavelet analysis shows the presence of several identifiable modes in the membrane and intracellular dynamics, and a double-wavelet analysis reveals nonlinear interactions between the regulatory processes in the form of mutual frequency and amplitude modulations.

Original language	English
Journal	Physical Review Letters
Volume	94
Issue number	21
Pages (from-to)	218103
ISSN	0031-9007
Publication status	Published - 3 Jun 2005

Keywords

Animals
Biophysical Phenomena
Biophysics
Electrophysiology
Ion Channels
Lymnaea
Microscopy, Interference
Models, Statistical
Neurons
Oscillometry
Time Factors

Cite this

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title = "Interference microscopy under double-wavelet analysis: a new approach to studying cell dynamics",

abstract = "This Letter combines a novel experimental approach to the study of intracellular processes with a newly developed technique for multimode time-series analysis. Experiments are performed on isolated pond snail (Lymnaea stagnalis) neurons. Local variations in the cellular refractive index as detected by laser interference microscopy are related to the processes in the cell. A wavelet analysis shows the presence of several identifiable modes in the membrane and intracellular dynamics, and a double-wavelet analysis reveals nonlinear interactions between the regulatory processes in the form of mutual frequency and amplitude modulations.",

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T1 - Interference microscopy under double-wavelet analysis: a new approach to studying cell dynamics

AU - Sosnovtseva, Olga

AU - Pavlov, A N

AU - Brazhe, Nadezda

AU - Brazhe, Alexey

AU - Erokhova, L A

AU - Maksimov, G V

AU - Mosekilde, Erik

PY - 2005/6/3

Y1 - 2005/6/3

N2 - This Letter combines a novel experimental approach to the study of intracellular processes with a newly developed technique for multimode time-series analysis. Experiments are performed on isolated pond snail (Lymnaea stagnalis) neurons. Local variations in the cellular refractive index as detected by laser interference microscopy are related to the processes in the cell. A wavelet analysis shows the presence of several identifiable modes in the membrane and intracellular dynamics, and a double-wavelet analysis reveals nonlinear interactions between the regulatory processes in the form of mutual frequency and amplitude modulations.

AB - This Letter combines a novel experimental approach to the study of intracellular processes with a newly developed technique for multimode time-series analysis. Experiments are performed on isolated pond snail (Lymnaea stagnalis) neurons. Local variations in the cellular refractive index as detected by laser interference microscopy are related to the processes in the cell. A wavelet analysis shows the presence of several identifiable modes in the membrane and intracellular dynamics, and a double-wavelet analysis reveals nonlinear interactions between the regulatory processes in the form of mutual frequency and amplitude modulations.

KW - Animals

KW - Biophysical Phenomena

KW - Biophysics

KW - Electrophysiology

KW - Ion Channels

KW - Lymnaea

KW - Microscopy, Interference

KW - Models, Statistical

KW - Neurons

KW - Oscillometry

KW - Time Factors

M3 - Journal article

C2 - 16090354

SN - 0031-9007

VL - 94

SP - 218103

JO - Physical Review Letters

JF - Physical Review Letters

IS - 21

ER -

Interference microscopy under double-wavelet analysis: a new approach to studying cell dynamics

Abstract

Keywords

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