Interactions of virulent and avirulent leptospires with primary cultures of renal epithelial cells.

S A Ballard; M Williamson; B Adler; T Vinh; S Faine

Interactions of virulent and avirulent leptospires with primary cultures of renal epithelial cells.

S A Ballard, M Williamson, B Adler, T Vinh, S Faine

Cell and Neurobiology

32 Citations (Scopus)

Abstract

A primary culture system for the cells of mouse renal-tubular epithelium was established and used to observe the adhesion of leptospires. Virulent strains of serovars copenhageni and ballum attached themselves to epithelial cells within 3 h of infection whereas an avirulent variant of serovar copenhageni did not adhere to epithelial cells at all within the experimental period of 24 h. The saprophytic Leptospira biflexa serovar patoc became attached non-specifically to inert glass surfaces as well as to the cells. The adhesion of leptospires to epithelial cells was not inhibited by homologous antibody.
Udgivelsesdato: 1986-Feb

Original language	English
Journal	Journal of Medical Microbiology
Volume	21
Issue number	1
Pages (from-to)	59-67
Number of pages	8
ISSN	0022-2615
Publication status	Published - 1986

Cite this

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title = "Interactions of virulent and avirulent leptospires with primary cultures of renal epithelial cells.",

abstract = "A primary culture system for the cells of mouse renal-tubular epithelium was established and used to observe the adhesion of leptospires. Virulent strains of serovars copenhageni and ballum attached themselves to epithelial cells within 3 h of infection whereas an avirulent variant of serovar copenhageni did not adhere to epithelial cells at all within the experimental period of 24 h. The saprophytic Leptospira biflexa serovar patoc became attached non-specifically to inert glass surfaces as well as to the cells. The adhesion of leptospires to epithelial cells was not inhibited by homologous antibody. Udgivelsesdato: 1986-Feb",

author = "Ballard, {S A} and M Williamson and B Adler and T Vinh and S Faine",

note = "Keywords: Adhesiveness; Animals; Antibodies, Bacterial; Antigen-Antibody Reactions; Cells, Cultured; Epithelium; Fluorescent Antibody Technique; Kidney Tubules; Leptospira; Mice; Microscopy, Electron, Scanning",

year = "1986",

language = "English",

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journal = "Journal of Medical Microbiology",

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T1 - Interactions of virulent and avirulent leptospires with primary cultures of renal epithelial cells.

AU - Ballard, S A

AU - Williamson, M

AU - Adler, B

AU - Vinh, T

AU - Faine, S

N1 - Keywords: Adhesiveness; Animals; Antibodies, Bacterial; Antigen-Antibody Reactions; Cells, Cultured; Epithelium; Fluorescent Antibody Technique; Kidney Tubules; Leptospira; Mice; Microscopy, Electron, Scanning

PY - 1986

Y1 - 1986

N2 - A primary culture system for the cells of mouse renal-tubular epithelium was established and used to observe the adhesion of leptospires. Virulent strains of serovars copenhageni and ballum attached themselves to epithelial cells within 3 h of infection whereas an avirulent variant of serovar copenhageni did not adhere to epithelial cells at all within the experimental period of 24 h. The saprophytic Leptospira biflexa serovar patoc became attached non-specifically to inert glass surfaces as well as to the cells. The adhesion of leptospires to epithelial cells was not inhibited by homologous antibody. Udgivelsesdato: 1986-Feb

AB - A primary culture system for the cells of mouse renal-tubular epithelium was established and used to observe the adhesion of leptospires. Virulent strains of serovars copenhageni and ballum attached themselves to epithelial cells within 3 h of infection whereas an avirulent variant of serovar copenhageni did not adhere to epithelial cells at all within the experimental period of 24 h. The saprophytic Leptospira biflexa serovar patoc became attached non-specifically to inert glass surfaces as well as to the cells. The adhesion of leptospires to epithelial cells was not inhibited by homologous antibody. Udgivelsesdato: 1986-Feb

M3 - Journal article

C2 - 3512834

SN - 0022-2615

VL - 21

SP - 59

EP - 67

JO - Journal of Medical Microbiology

JF - Journal of Medical Microbiology

IS - 1

ER -