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Inhibition of human Chk1 causes increased initiation of DNA replication, phosphorylation of ATR targets, and DNA breakage.
Randi G Syljuåsen, Claus Storgaard Sørensen, Lasse Tengbjerg Hansen, Kasper Fugger, Cecilia Lundin, Fredrik Johansson, Thomas Helleday, Maxwell Sehested, Jiri Lukas, Jiri Bartek