Informed choice about Down syndrome screening - effect of an eHealth tool: a randomized controlled trial

Mette M Skjøth; Eva Draborg; Ronald F Lamont; Claus D Pedersen; Helle P Hansen; Claus T Ekstrøm; Jan S Jørgensen

doi:10.1111/aogs.12758

Informed choice about Down syndrome screening - effect of an eHealth tool: a randomized controlled trial

Mette M Skjøth, Eva Draborg, Ronald F Lamont, Claus D Pedersen, Helle P Hansen, Claus T Ekstrøm, Jan S Jørgensen

Section of Biostatistics

4 Citations (Scopus)

Abstract

INTRODUCTION: The aim of this study was to evaluate the effect of an eHealth intervention (interactive website) on pregnant women's ability to make an informed choice about Down syndrome screening.

MATERIAL AND METHODS: The study was designed as a randomized controlled trial with allocation to an intervention group and a control group in a ratio of 1:1. Subsequent subgroup analysis was conducted. Participants were recruited from 5 August 2013 to 25 April 2014 at Odense University Hospital, Denmark. Inclusion criteria were: pregnant women aged ≥18 years who were invited to participate in Down syndrome screening. Exclusion criteria were: high risk of abortion, psycho-socially vulnerable women, late referral, inability to speak Danish and women declining to participate. The primary outcome was informed choice about Down syndrome screening. The Multidimensional Measure of Informed Choice was used to assess whether the choice was informed or uninformed.

RESULTS: A total of 1150 participants were included in the study, of which 910 (79%) completed the questionnaire. Only a minority (30% of the women in the intervention group) actually used the website. There was no significant difference in the groups with respect to making an informed choice. The mean knowledge scores were significantly higher for those in the intervention group who used the intervention.

CONCLUSIONS: An interactive website with information about Down syndrome screening had no direct effect on making an informed choice. However, the majority of the pregnant women who used the website were satisfied with the website and would recommend it to others.

Original language	English
Journal	Acta Obstetricia et Gynecologica Scandinavica
Volume	94
Issue number	12
Pages (from-to)	1327-1336
Number of pages	10
ISSN	0001-6349
DOIs	https://doi.org/10.1111/aogs.12758
Publication status	Published - 1 Dec 2015

Keywords

Adult
Choice Behavior
Denmark
Down Syndrome
Female
Humans
Pregnancy
Prenatal Diagnosis
Surveys and Questionnaires
Telemedicine
Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

Access to Document

10.1111/aogs.12758

https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/aogs.12758

Cite this

@article{45adc6a5d06a4b48a13fa221a9b904f7,

title = "Informed choice about Down syndrome screening - effect of an eHealth tool: a randomized controlled trial",

abstract = "INTRODUCTION: The aim of this study was to evaluate the effect of an eHealth intervention (interactive website) on pregnant women's ability to make an informed choice about Down syndrome screening.MATERIAL AND METHODS: The study was designed as a randomized controlled trial with allocation to an intervention group and a control group in a ratio of 1:1. Subsequent subgroup analysis was conducted. Participants were recruited from 5 August 2013 to 25 April 2014 at Odense University Hospital, Denmark. Inclusion criteria were: pregnant women aged ≥18 years who were invited to participate in Down syndrome screening. Exclusion criteria were: high risk of abortion, psycho-socially vulnerable women, late referral, inability to speak Danish and women declining to participate. The primary outcome was informed choice about Down syndrome screening. The Multidimensional Measure of Informed Choice was used to assess whether the choice was informed or uninformed.RESULTS: A total of 1150 participants were included in the study, of which 910 (79%) completed the questionnaire. Only a minority (30% of the women in the intervention group) actually used the website. There was no significant difference in the groups with respect to making an informed choice. The mean knowledge scores were significantly higher for those in the intervention group who used the intervention.CONCLUSIONS: An interactive website with information about Down syndrome screening had no direct effect on making an informed choice. However, the majority of the pregnant women who used the website were satisfied with the website and would recommend it to others.",

keywords = "Adult, Choice Behavior, Denmark, Down Syndrome, Female, Humans, Pregnancy, Prenatal Diagnosis, Surveys and Questionnaires, Telemedicine, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't",

author = "Skj{\o}th, {Mette M} and Eva Draborg and Lamont, {Ronald F} and Pedersen, {Claus D} and Hansen, {Helle P} and Ekstr{\o}m, {Claus T} and J{\o}rgensen, {Jan S}",

note = "{\textcopyright} 2015 Nordic Federation of Societies of Obstetrics and Gynecology.",

year = "2015",

month = dec,

day = "1",

doi = "10.1111/aogs.12758",

language = "English",

volume = "94",

pages = "1327--1336",

journal = "Acta Obstetricia et Gynecologica Scandinavica",

issn = "0001-6349",

publisher = "JohnWiley & Sons Ltd",

number = "12",

}

TY - JOUR

T1 - Informed choice about Down syndrome screening - effect of an eHealth tool

T2 - a randomized controlled trial

AU - Skjøth, Mette M

AU - Draborg, Eva

AU - Lamont, Ronald F

AU - Pedersen, Claus D

AU - Hansen, Helle P

AU - Ekstrøm, Claus T

AU - Jørgensen, Jan S

PY - 2015/12/1

Y1 - 2015/12/1

N2 - INTRODUCTION: The aim of this study was to evaluate the effect of an eHealth intervention (interactive website) on pregnant women's ability to make an informed choice about Down syndrome screening.MATERIAL AND METHODS: The study was designed as a randomized controlled trial with allocation to an intervention group and a control group in a ratio of 1:1. Subsequent subgroup analysis was conducted. Participants were recruited from 5 August 2013 to 25 April 2014 at Odense University Hospital, Denmark. Inclusion criteria were: pregnant women aged ≥18 years who were invited to participate in Down syndrome screening. Exclusion criteria were: high risk of abortion, psycho-socially vulnerable women, late referral, inability to speak Danish and women declining to participate. The primary outcome was informed choice about Down syndrome screening. The Multidimensional Measure of Informed Choice was used to assess whether the choice was informed or uninformed.RESULTS: A total of 1150 participants were included in the study, of which 910 (79%) completed the questionnaire. Only a minority (30% of the women in the intervention group) actually used the website. There was no significant difference in the groups with respect to making an informed choice. The mean knowledge scores were significantly higher for those in the intervention group who used the intervention.CONCLUSIONS: An interactive website with information about Down syndrome screening had no direct effect on making an informed choice. However, the majority of the pregnant women who used the website were satisfied with the website and would recommend it to others.

AB - INTRODUCTION: The aim of this study was to evaluate the effect of an eHealth intervention (interactive website) on pregnant women's ability to make an informed choice about Down syndrome screening.MATERIAL AND METHODS: The study was designed as a randomized controlled trial with allocation to an intervention group and a control group in a ratio of 1:1. Subsequent subgroup analysis was conducted. Participants were recruited from 5 August 2013 to 25 April 2014 at Odense University Hospital, Denmark. Inclusion criteria were: pregnant women aged ≥18 years who were invited to participate in Down syndrome screening. Exclusion criteria were: high risk of abortion, psycho-socially vulnerable women, late referral, inability to speak Danish and women declining to participate. The primary outcome was informed choice about Down syndrome screening. The Multidimensional Measure of Informed Choice was used to assess whether the choice was informed or uninformed.RESULTS: A total of 1150 participants were included in the study, of which 910 (79%) completed the questionnaire. Only a minority (30% of the women in the intervention group) actually used the website. There was no significant difference in the groups with respect to making an informed choice. The mean knowledge scores were significantly higher for those in the intervention group who used the intervention.CONCLUSIONS: An interactive website with information about Down syndrome screening had no direct effect on making an informed choice. However, the majority of the pregnant women who used the website were satisfied with the website and would recommend it to others.

KW - Adult

KW - Choice Behavior

KW - Denmark

KW - Down Syndrome

KW - Female

KW - Humans

KW - Pregnancy

KW - Prenatal Diagnosis

KW - Surveys and Questionnaires

KW - Telemedicine

KW - Journal Article

KW - Randomized Controlled Trial

KW - Research Support, Non-U.S. Gov't

U2 - 10.1111/aogs.12758

DO - 10.1111/aogs.12758

M3 - Journal article

C2 - 26332592

SN - 0001-6349

VL - 94

SP - 1327

EP - 1336

JO - Acta Obstetricia et Gynecologica Scandinavica

JF - Acta Obstetricia et Gynecologica Scandinavica

IS - 12

ER -

Informed choice about Down syndrome screening - effect of an eHealth tool: a randomized controlled trial

Abstract

Keywords

Access to Document

Fingerprint

Cite this