Abstract
The present invention relates to a method of inducing cancer cells into dormancy and treating cancer in a subject. This method involves administering to a subject an effective amount of a compound that disrupts interaction between urokinase plasminogen activator receptor and integrin, thereby including cancer cells into dormancy and treating cancer in the subject. Also disclosed is a method of disrupting interaction between integrin and urokinase plasminogen activator receptor on cancer cells. The present invention also relates to a method of screening for compounds effective in inducing tumor dormancy and treating cancer in a subject.
| Original language | English |
|---|---|
| IPC | G06G 7/ 60 A I |
| Patent number | US2010249184 |
| Country/Territory | Denmark |
| Priority date | 17/03/2008 |
| Priority number | US20080531502 |
| Publication status | Published - 30 Sept 2010 |
