Individualisering af behandling af osteoartikulære infektioner hos børn kan afkorte behandlingsforløbet

TY - JOUR

T1 - Individualisering af behandling af osteoartikulære infektioner hos børn kan afkorte behandlingsforløbet

AU - Kristensen, Kim

AU - Andersen, Jesper

AU - Hansen, Kjeld Gade

AU - Hoffmann, Thomas

AU - Kurtzhals, Jørgen

AU - Nygaard, Ulrikka

AU - Pedersen, Freddy Karup

PY - 2014/7/21

Y1 - 2014/7/21

N2 - Older studies have suggested that antibiotic treatment for less than 21 days in children with osteoarticular infections is associated with relapse, and therefore traditionally these infections have been treated for six weeks with an intravenous phase of one week. However, four new prospective studies suggest that if the duration of treatment is individualized and made dependent on the clinical response and the C-reactive protein level, the treatment course may be shortened substantially without increasing the risk of relapse or sequelae. This article reviews older and newer literature on this subject.

AB - Older studies have suggested that antibiotic treatment for less than 21 days in children with osteoarticular infections is associated with relapse, and therefore traditionally these infections have been treated for six weeks with an intravenous phase of one week. However, four new prospective studies suggest that if the duration of treatment is individualized and made dependent on the clinical response and the C-reactive protein level, the treatment course may be shortened substantially without increasing the risk of relapse or sequelae. This article reviews older and newer literature on this subject.

M3 - Tidsskriftartikel

C2 - 25292233

SN - 0041-5782

VL - 176

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

IS - 30

ER -