Increase in neurogenesis and behavioural benefit after chronic fluoxetine treatment in Wistar rats

Anders Bue Klein; P Flagstad; P E G Kristjansen; F F Johansen; U Englund

doi:10.1111/j.1600-0404.2007.00910.x

Increase in neurogenesis and behavioural benefit after chronic fluoxetine treatment in Wistar rats

Anders Bue Klein, P Flagstad, P E G Kristjansen, F F Johansen, U Englund

Nutritional Immunology

66 Citations (Scopus)

Abstract

Disturbances in hippocampal neurogenesis may be involved in the pathophysiology of depression and it has been argued that an increase in the generation of new nerve cells in the hippocampus is involved in the mechanism of action of antidepressants.

Original language	English
Journal	Acta Neurologica Scandinavica
Volume	117
Issue number	2
Pages (from-to)	94-100
Number of pages	7
ISSN	0001-6314
DOIs	https://doi.org/10.1111/j.1600-0404.2007.00910.x
Publication status	Published - Feb 2008

Keywords

Animals
Behavior, Animal
Bromodeoxyuridine
Cell Count
Cell Proliferation
Dentate Gyrus
Drug Administration Schedule
Feeding Behavior
Fluoxetine
Ki-67 Antigen
Male
Microtubule-Associated Proteins
Neurons
Neuropeptides
Rats
Rats, Wistar
Reaction Time
Serotonin Uptake Inhibitors

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10.1111/j.1600-0404.2007.00910.x

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title = "Increase in neurogenesis and behavioural benefit after chronic fluoxetine treatment in Wistar rats",

abstract = "Disturbances in hippocampal neurogenesis may be involved in the pathophysiology of depression and it has been argued that an increase in the generation of new nerve cells in the hippocampus is involved in the mechanism of action of antidepressants.",

keywords = "Animals, Behavior, Animal, Bromodeoxyuridine, Cell Count, Cell Proliferation, Dentate Gyrus, Drug Administration Schedule, Feeding Behavior, Fluoxetine, Ki-67 Antigen, Male, Microtubule-Associated Proteins, Neurons, Neuropeptides, Rats, Rats, Wistar, Reaction Time, Serotonin Uptake Inhibitors",

author = "Klein, {Anders Bue} and P Flagstad and Kristjansen, {P E G} and Johansen, {F F} and U Englund",

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AU - Klein, Anders Bue

AU - Flagstad, P

AU - Kristjansen, P E G

AU - Johansen, F F

AU - Englund, U

PY - 2008/2

Y1 - 2008/2

N2 - Disturbances in hippocampal neurogenesis may be involved in the pathophysiology of depression and it has been argued that an increase in the generation of new nerve cells in the hippocampus is involved in the mechanism of action of antidepressants.

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KW - Animals

KW - Behavior, Animal

KW - Bromodeoxyuridine

KW - Cell Count

KW - Cell Proliferation

KW - Dentate Gyrus

KW - Drug Administration Schedule

KW - Feeding Behavior

KW - Fluoxetine

KW - Ki-67 Antigen

KW - Male

KW - Microtubule-Associated Proteins

KW - Neurons

KW - Neuropeptides

KW - Rats

KW - Rats, Wistar

KW - Reaction Time

KW - Serotonin Uptake Inhibitors

U2 - 10.1111/j.1600-0404.2007.00910.x

DO - 10.1111/j.1600-0404.2007.00910.x

M3 - Journal article

C2 - 18184344

SN - 0001-6314

VL - 117

SP - 94

EP - 100

JO - Acta Neurologica Scandinavica

JF - Acta Neurologica Scandinavica

IS - 2

ER -

Increase in neurogenesis and behavioural benefit after chronic fluoxetine treatment in Wistar rats

Abstract

Keywords

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