Incidence of pancreatic cancer in Denmark: 70 years of registration, 1943-2012

Tanja Cruusberg Weble; Jon Kroll Bjerregaard; Peter Kissmeyer; Mogens Vyberg; Carsten Palnaes Hansen; Niels Henrik Holländer; Christoffer Johansen

doi:10.1080/0284186x.2017.1351036

Incidence of pancreatic cancer in Denmark: 70 years of registration, 1943-2012

Tanja Cruusberg Weble, Jon Kroll Bjerregaard, Peter Kissmeyer, Mogens Vyberg, Carsten Palnaes Hansen, Niels Henrik Holländer, Christoffer Johansen

Department of Clinical Medicine

4 Citations (Scopus)

Abstract

BACKGROUND: The aim of this study was to monitor the evolution of the incidence of pancreatic cancer in Denmark over 70 years. We also compared registrations of pancreatic cancer in a nationwide population-based database, the Danish Cancer Registry, and a clinical database, the Danish Pancreatic Cancer Database, in 2012-2013.

MATERIAL AND METHODS: Registrations of pancreatic cancer from the Danish Cancer Registry over 1943-2012 were used to calculate age-specific incidence rates per 100 000 person years by sex and age in 5-year period, weighted by the Segi World Standard Population for age standardization. We used absolute numbers from the Cancer Registry and the Pancreatic Cancer Database, including distribution of topography of cancers registered in 2012-2013, to compare registration in the two data sources.

RESULTS: The incidence rates of pancreatic cancer among Danish men increased until 1968-1972, when a decrease was observed until the mid-1990s. A similar peak was observed in women a decade later but generally at lower incidence. After the mid-1990s, the incidence rates for both sexes increased until the end of the study period. In our comparison of registrations in the Cancer Registry and the Pancreatic Cancer Database in 2012-2013, we found that 29% of the incident cases registered in the Cancer Registry were not in the Database; and 11% of the incident cases registered in the Database, were not registered in the Cancer Registry.

CONCLUSIONS: The incidence of pancreatic cancer increased steadily during the last 20 years of our study period in both sexes. The differences in registration of incident cases in the Cancer Registry and in the Pancreatic Cancer Database indicate underreporting of incident cases of pancreatic cancer in Denmark. The magnitude of this underreporting cannot be estimated based on this data.

Original language	English
Journal	Acta Oncologica
Volume	56
Issue number	12
Pages (from-to)	1763-1768
ISSN	0284-186X
DOIs	https://doi.org/10.1080/0284186x.2017.1351036
Publication status	Published - 2 Dec 2017

Keywords

Adult
Age Distribution
Aged
Aged, 80 and over
Carcinoma, Pancreatic Ductal/epidemiology
Denmark/epidemiology
Female
Humans
Incidence
Male
Middle Aged
Pancreatic Neoplasms/epidemiology
Registries

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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Cite this

@article{3cb4720f84ba482abf1af66a15dd62de,

title = "Incidence of pancreatic cancer in Denmark: 70 years of registration, 1943-2012",

abstract = "BACKGROUND: The aim of this study was to monitor the evolution of the incidence of pancreatic cancer in Denmark over 70 years. We also compared registrations of pancreatic cancer in a nationwide population-based database, the Danish Cancer Registry, and a clinical database, the Danish Pancreatic Cancer Database, in 2012-2013.MATERIAL AND METHODS: Registrations of pancreatic cancer from the Danish Cancer Registry over 1943-2012 were used to calculate age-specific incidence rates per 100 000 person years by sex and age in 5-year period, weighted by the Segi World Standard Population for age standardization. We used absolute numbers from the Cancer Registry and the Pancreatic Cancer Database, including distribution of topography of cancers registered in 2012-2013, to compare registration in the two data sources.RESULTS: The incidence rates of pancreatic cancer among Danish men increased until 1968-1972, when a decrease was observed until the mid-1990s. A similar peak was observed in women a decade later but generally at lower incidence. After the mid-1990s, the incidence rates for both sexes increased until the end of the study period. In our comparison of registrations in the Cancer Registry and the Pancreatic Cancer Database in 2012-2013, we found that 29% of the incident cases registered in the Cancer Registry were not in the Database; and 11% of the incident cases registered in the Database, were not registered in the Cancer Registry.CONCLUSIONS: The incidence of pancreatic cancer increased steadily during the last 20 years of our study period in both sexes. The differences in registration of incident cases in the Cancer Registry and in the Pancreatic Cancer Database indicate underreporting of incident cases of pancreatic cancer in Denmark. The magnitude of this underreporting cannot be estimated based on this data.",

keywords = "Adult, Age Distribution, Aged, Aged, 80 and over, Carcinoma, Pancreatic Ductal/epidemiology, Denmark/epidemiology, Female, Humans, Incidence, Male, Middle Aged, Pancreatic Neoplasms/epidemiology, Registries",

author = "Weble, {Tanja Cruusberg} and Bjerregaard, {Jon Kroll} and Peter Kissmeyer and Mogens Vyberg and Hansen, {Carsten Palnaes} and Holl{\"a}nder, {Niels Henrik} and Christoffer Johansen",

year = "2017",

month = dec,

day = "2",

doi = "10.1080/0284186x.2017.1351036",

language = "English",

volume = "56",

pages = "1763--1768",

journal = "Acta Oncologica, Supplement",

issn = "1100-1704",

publisher = "Taylor & Francis",

number = "12",

}

TY - JOUR

T1 - Incidence of pancreatic cancer in Denmark

T2 - 70 years of registration, 1943-2012

AU - Weble, Tanja Cruusberg

AU - Bjerregaard, Jon Kroll

AU - Kissmeyer, Peter

AU - Vyberg, Mogens

AU - Hansen, Carsten Palnaes

AU - Holländer, Niels Henrik

AU - Johansen, Christoffer

PY - 2017/12/2

Y1 - 2017/12/2

N2 - BACKGROUND: The aim of this study was to monitor the evolution of the incidence of pancreatic cancer in Denmark over 70 years. We also compared registrations of pancreatic cancer in a nationwide population-based database, the Danish Cancer Registry, and a clinical database, the Danish Pancreatic Cancer Database, in 2012-2013.MATERIAL AND METHODS: Registrations of pancreatic cancer from the Danish Cancer Registry over 1943-2012 were used to calculate age-specific incidence rates per 100 000 person years by sex and age in 5-year period, weighted by the Segi World Standard Population for age standardization. We used absolute numbers from the Cancer Registry and the Pancreatic Cancer Database, including distribution of topography of cancers registered in 2012-2013, to compare registration in the two data sources.RESULTS: The incidence rates of pancreatic cancer among Danish men increased until 1968-1972, when a decrease was observed until the mid-1990s. A similar peak was observed in women a decade later but generally at lower incidence. After the mid-1990s, the incidence rates for both sexes increased until the end of the study period. In our comparison of registrations in the Cancer Registry and the Pancreatic Cancer Database in 2012-2013, we found that 29% of the incident cases registered in the Cancer Registry were not in the Database; and 11% of the incident cases registered in the Database, were not registered in the Cancer Registry.CONCLUSIONS: The incidence of pancreatic cancer increased steadily during the last 20 years of our study period in both sexes. The differences in registration of incident cases in the Cancer Registry and in the Pancreatic Cancer Database indicate underreporting of incident cases of pancreatic cancer in Denmark. The magnitude of this underreporting cannot be estimated based on this data.

AB - BACKGROUND: The aim of this study was to monitor the evolution of the incidence of pancreatic cancer in Denmark over 70 years. We also compared registrations of pancreatic cancer in a nationwide population-based database, the Danish Cancer Registry, and a clinical database, the Danish Pancreatic Cancer Database, in 2012-2013.MATERIAL AND METHODS: Registrations of pancreatic cancer from the Danish Cancer Registry over 1943-2012 were used to calculate age-specific incidence rates per 100 000 person years by sex and age in 5-year period, weighted by the Segi World Standard Population for age standardization. We used absolute numbers from the Cancer Registry and the Pancreatic Cancer Database, including distribution of topography of cancers registered in 2012-2013, to compare registration in the two data sources.RESULTS: The incidence rates of pancreatic cancer among Danish men increased until 1968-1972, when a decrease was observed until the mid-1990s. A similar peak was observed in women a decade later but generally at lower incidence. After the mid-1990s, the incidence rates for both sexes increased until the end of the study period. In our comparison of registrations in the Cancer Registry and the Pancreatic Cancer Database in 2012-2013, we found that 29% of the incident cases registered in the Cancer Registry were not in the Database; and 11% of the incident cases registered in the Database, were not registered in the Cancer Registry.CONCLUSIONS: The incidence of pancreatic cancer increased steadily during the last 20 years of our study period in both sexes. The differences in registration of incident cases in the Cancer Registry and in the Pancreatic Cancer Database indicate underreporting of incident cases of pancreatic cancer in Denmark. The magnitude of this underreporting cannot be estimated based on this data.

KW - Adult

KW - Age Distribution

KW - Aged

KW - Aged, 80 and over

KW - Carcinoma, Pancreatic Ductal/epidemiology

KW - Denmark/epidemiology

KW - Female

KW - Humans

KW - Incidence

KW - Male

KW - Middle Aged

KW - Pancreatic Neoplasms/epidemiology

KW - Registries

U2 - 10.1080/0284186x.2017.1351036

DO - 10.1080/0284186x.2017.1351036

M3 - Journal article

C2 - 28741399

SN - 1100-1704

VL - 56

SP - 1763

EP - 1768

JO - Acta Oncologica, Supplement

JF - Acta Oncologica, Supplement

IS - 12

ER -

Incidence of pancreatic cancer in Denmark: 70 years of registration, 1943-2012

Abstract

Keywords

UN SDGs

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