Abstract
Background: Sinonasal cancers are rare and comprise <1% of all malignancies. This study describes incidence and survival in sinonasal carcinomas in Denmark from 1980 to 2014. Methods: All patients registered in the Danish Cancer Registry in the period were included. Age-adjusted incidence rate, average annual percentage change, and relative survival were calculated. Age-period-cohort models were constructed. Results: 1,720 patients with sinonasal carcinoma (median age 67 years, 63% males) were identified. There was no significant change in age-adjusted incidence; 0.70 in 1980 to 0.43 per 100,000 in 2014 (p >.05). Relative 5- and 10-year survival were 52% and 40% for men, 58% and 42% for women. An increase in 5-year survival from 1980 to 2014 from 46% to 65% (p <.05) was found. Nasal carcinomas had a significantly better relative survival compared to sinus carcinoma, as did squamous cell carcinomas when compared to neuroendocrine malignancies. Conclusion: In Denmark between 1980 and 2014, the incidence of sinonasal carcinomas has been stable and the relative survival has increased significantly.
| Original language | English |
|---|---|
| Journal | Acta Oncologica |
| Volume | 57 |
| Issue number | 9 |
| Pages (from-to) | 1152-1158 |
| Number of pages | 7 |
| ISSN | 0284-186X |
| DOIs | |
| Publication status | Published - 2 Sept 2018 |
Keywords
- Adolescent
- Adult
- Age Distribution
- Aged
- Aged, 80 and over
- Carcinoma, Squamous Cell/epidemiology
- Child
- Child, Preschool
- Denmark/epidemiology
- Female
- Humans
- Incidence
- Male
- Middle Aged
- Paranasal Sinus Neoplasms/epidemiology
- Registries
- Survival Analysis
- Survival Rate/trends
- Time Factors
- Young Adult
